| Entry |
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| Name | Bupropion hydrochloride (JAN/USP); Wellbutrin (TN); Zyban (TN) | ||||||||||
| Product | FORFIVO (Almatica Pharma), WELLBUTRIN (Bausch Health US LLC), WELLBUTRIN (GlaxoSmithKline LLC) | ||||||||||
| Generic | BUPROPION (Proficient Rx LP), BUPROPION (Zydus Lifesciences Limited), BUPROPION (Zydus Pharmaceuticals (USA)), BUPROPION HCL ER (Direct_Rx), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (SR) (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (XL) (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (SR) (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (A-S Medication Solutions), BUPROPION HYDROCHLORIDE (Accord Healthcare), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Actavis Pharma), BUPROPION HYDROCHLORIDE (Alembic Pharmaceuticals Limited), BUPROPION HYDROCHLORIDE (Alvogen), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (American Health Packaging), BUPROPION HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), BUPROPION HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), BUPROPION HYDROCHLORIDE (Apnar Pharma LP), BUPROPION HYDROCHLORIDE (Apotex Corp), BUPROPION HYDROCHLORIDE (AvPAK), BUPROPION HYDROCHLORIDE (AvPAK), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (BluePoint Laboratories), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (XL) (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (SR) (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (Bryant Ranch Prepack), BUPROPION HYDROCHLORIDE (CIPLA USA INC.,), BUPROPION HYDROCHLORIDE (CIPLA USA INC.,), BUPROPION HYDROCHLORIDE (Cadila Pharmaceuticals Limited), BUPROPION HYDROCHLORIDE (Cardinal Health), BUPROPION HYDROCHLORIDE (Cardinal Health 107), BUPROPION HYDROCHLORIDE (SR) (Cipla USA Inc.,), BUPROPION HYDROCHLORIDE (Clinical Solutions Wholesale), BUPROPION HYDROCHLORIDE (Clinical Solutions Wholesale), BUPROPION HYDROCHLORIDE (DIRECT RX), BUPROPION HYDROCHLORIDE (DIRECT RX), BUPROPION HYDROCHLORIDE (SR) (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (XL) (Denton Pharma), BUPROPION HYDROCHLORIDE (XL) (Denton Pharma), BUPROPION HYDROCHLORIDE (Denton Pharma), BUPROPION HYDROCHLORIDE (DirectRX), BUPROPION HYDROCHLORIDE (Direct_Rx), BUPROPION HYDROCHLORIDE (Direct_Rx), BUPROPION HYDROCHLORIDE (Dr Reddys Laboratories), BUPROPION HYDROCHLORIDE (SR) (Dr. Reddy's Laboratories), BUPROPION HYDROCHLORIDE (Dr. Reddy's Laboratories), BUPROPION HYDROCHLORIDE (Dr. Reddy's Laboratories), BUPROPION HYDROCHLORIDE (Eon Labs), BUPROPION HYDROCHLORIDE (Epic Pharma LLC), BUPROPION HYDROCHLORIDE (Epic Pharma), BUPROPION HYDROCHLORIDE (Exelan Pharmaceuticals), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Golden State Medical Supply), BUPROPION HYDROCHLORIDE (Graviti Pharmaceuticals Private Limited), BUPROPION HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), BUPROPION HYDROCHLORIDE (XL) (Lannett Company), BUPROPION HYDROCHLORIDE (Lupin Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE (Major Pharmaceuticals), BUPROPION HYDROCHLORIDE EXTENDED RELEASE (Marlex Pharmaceuticals), BUPROPION HYDROCHLORIDE (Medsource Pharmaceuticals), BUPROPION HYDROCHLORIDE (SR) (Medsource Pharmaceuticals), BUPROPION HYDROCHLORIDE (Method Pharmaceuticals), BUPROPION HYDROCHLORIDE (Method Pharmaceuticals), BUPROPION HYDROCHLORIDE (Micro Labs Limited), BUPROPION HYDROCHLORIDE (Modavar Pharmaceuticals LLC), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION HYDROCHLORIDE (NCS HealthCare of KY), BUPROPION (Northwind Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (NuCare Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (PD-Rx Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Preferred Pharmaceuticals), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (XL) (Proficient Rx LP), BUPROPION HYDROCHLORIDE (XL) (Proficient Rx LP), BUPROPION (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Proficient Rx LP), BUPROPION HYDROCHLORIDE (Quality Care Products), BUPROPION HYDROCHLORIDE (Quality Care Products), BUPROPION HYDROCHLORIDE (Quality Care Products), BUPROPION HYDROCHLORIDE (Quality Care Products), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (XL) (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (REMEDYREPACK), BUPROPION HYDROCHLORIDE (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (XL) (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (SR) (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (XL) (RPK Pharmaceuticals), BUPROPION HYDROCHLORIDE (Radha Pharmaceuticals), BUPROPION HYDROCHLORIDE (Rising Pharma Holdings), BUPROPION HYDROCHLORIDE (Rising Pharmaceuticals), BUPROPION HYDROCHLORIDE (XL) (Sandoz), BUPROPION HYDROCHLORIDE (ScieGen Pharmaceuticals), BUPROPION HYDROCHLORIDE (ScieGen Pharmaceuticals), BUPROPION HYDROCHLORIDE (ScieGen Pharmaceuticals), BUPROPION HYDROCHLORIDE (Slate Run Pharmaceuticals), BUPROPION HYDROCHLORIDE (Slate Run Pharmaceuticals), BUPROPION (Solco Healthcare US LLC), BUPROPION HYDROCHLORIDE (Sun Pharmaceutical Industries), BUPROPION HYDROCHLORIDE (Sun Pharmaceutical Industries), BUPROPION HYDROCHLORIDE (Sun Pharmaceutical Industries), BUPROPION HYDROCHLORIDE (Sun Pharmaceutical Industries), BUPROPION HYDROCHLORIDE (TWi Pharmaceuticals), BUPROPION HYDROCHLORIDE (TruPharma LLC), BUPROPION HYDROCHLORIDE (Westminster Pharmaceuticals), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), BUPROPION HYDROCHLORIDE (Wockhardt USA LLC.), BUPROPION HYDROCHLORIDE (medsource pharmaceuticals), BUPROPION HYDROCHLORIDE (XL) (DIRECT RX), BUPROPION HYDROCHLORIDE SR (DirectRx), BUPROPION HYDROCHLORIDE (Graviti Pharmaceuticals Private Limited) | ||||||||||
| Formula | C13H18ClNO. HCl | ||||||||||
| Exact mass | 275.0844 | ||||||||||
| Mol weight | 276.2021 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Neuropsychiatric agent DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI) | ||||||||||
| Remark |
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| Efficacy | Antidepressant, Noradrenalin and dopamine reuptake inhibitor | ||||||||||
| Disease | Major depressive disorder [DS:H01646] | ||||||||||
| Target | SLC6A2 (NAT1) [HSA:6530] [KO:K05035] SLC6A3 (DAT1) [HSA:6531] [KO:K05036] | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] N NERVOUS SYSTEM N06 PSYCHOANALEPTICS N06A ANTIDEPRESSANTS N06AX Other antidepressants N06AX12 Bupropion D00817 Bupropion hydrochloride (JAN/USP) <US> USP drug classification [BR:br08302] Anti-Addiction/Substance Abuse Treatment Agents Smoking Cessation Agents Bupropion D00817 Bupropion hydrochloride (JAN/USP) Antidepressants Antidepressants, Other Bupropion D00817 Bupropion hydrochloride (JAN/USP) Drug groups [BR:br08330] Neuropsychiatric agent DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI) DG00957 Bupropion D00817 Bupropion hydrochloride Target-based classification of drugs [BR:br08310] Transporters Solute carrier family SLC6 SLC6A2 (NAT1) D00817 Bupropion hydrochloride (JAN/USP) <US> SLC6A3 (DAT1) D00817 Bupropion hydrochloride (JAN/USP) <US> Drug groups [BR:br08330] Neuropsychiatric agent DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI) DG00957 Bupropion | ||||||||||
| Other DBs |
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| KCF data | ATOM 17 1 C8y C 15.4700 -16.1700 2 C5a C 16.7300 -15.4700 3 C8x C 14.2800 -15.4700 4 C8x C 15.4700 -17.5700 5 C1c C 17.9200 -16.1700 6 O5a O 16.7300 -14.0700 7 C8y C 13.0900 -16.1700 8 C8x C 14.2800 -18.2700 9 N1b N 19.1100 -15.4700 10 C1a C 17.9200 -17.5700 11 C8x C 13.0900 -17.5700 12 X Cl 11.9000 -15.4700 13 C1d C 20.3700 -16.1700 14 C1a C 21.5600 -15.4700 15 C1a C 20.3700 -17.5700 16 C1a C 21.5600 -16.9400 17 X Cl 25.3400 -15.4700 BOND 16 1 1 2 1 2 1 3 2 3 1 4 1 4 2 5 1 5 2 6 2 6 3 7 1 7 4 8 2 8 5 9 1 9 5 10 1 10 7 11 2 11 7 12 1 12 9 13 1 13 13 14 1 14 13 15 1 15 13 16 1 16 8 11 1 |