Oxymorphone hydrochloride

Entry

D00844                      Drug

Name

Oxymorphone hydrochloride (USP);
Numorphan (TN);
Opana (TN)

Product

Generic

OXYMORPHONE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), OXYMORPHONE HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), OXYMORPHONE HYDROCHLORIDE (Aurolife Pharma), OXYMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYMORPHONE HYDROCHLORIDE (Bryant Ranch Prepack), OXYMORPHONE HYDROCHLORIDE (Camber Pharmaceuticals), OXYMORPHONE HYDROCHLORIDE (Epic Pharma), OXYMORPHONE HYDROCHLORIDE (KVK-Tech), OXYMORPHONE HYDROCHLORIDE (Lake Erie Medical DBA Quality Care Products LLC), OXYMORPHONE HYDROCHLORIDE (Quality Care Products), OXYMORPHONE HYDROCHLORIDE (West-Ward Pharmaceuticals Corp.), OXYMORPHONE HYDROCHLORIDE (XLCare Pharmaceuticals)

Formula

C17H19NO4. HCl

Exact mass

337.1081

Mol weight

337.798

Structure

Simcomp

Class

Neuropsychiatric agent
DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
DG01984  Opioid analgesics

Remark

ATC code:

N02AA11

Chemical structure group:

DG01343

Product (DG01343):

D00844<US>

Efficacy

Analgesic (narcotic), Opioid receptor agonist

Target

OPRM1 [HSA:4988] [KO:K04215]

Pathway

hsa04080

Neuroactive ligand-receptor interaction

Interaction

Structure map

map07039

Opioid analgesics

map07224

Opioid receptor agonists/antagonists

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N02 ANALGESICS
   N02A OPIOIDS
    N02AA Natural opium alkaloids
     N02AA11 Oxymorphone
      D00844  Oxymorphone hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Analgesics
  Opioid Analgesics, Long-acting
   Oxymorphone
    D00844  Oxymorphone hydrochloride (USP)
  Opioid Analgesics, Short-acting
   Oxymorphone
    D00844  Oxymorphone hydrochloride (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG01343  Oxymorphone
     D00844  Oxymorphone hydrochloride
Analgesic
  DG01984  Opioid analgesics
   DG01343  Oxymorphone
    D00844  Oxymorphone hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D00844  Oxymorphone hydrochloride (USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG01343  Oxymorphone
Analgesic
  DG01984  Opioid analgesics
   DG01343  Oxymorphone

Other DBs

CAS:

357-07-3

PubChem:

7847909

ChEBI:

7866

LigandBox:

D00844

NIKKAJI:

J219.953J

KCF data

ATOM        23
            1   X   Cl   28.8996  -15.0125
            2   C1z C    23.5917  -17.6850
            3   C8y C    23.5857  -16.3337
            4   C1z C    24.7573  -18.3521
            5   C1y C    22.4376  -18.3637
            6   C8y C    22.4201  -15.6610
            7   C8y C    24.7515  -15.6610
            8   C1y C    25.9174  -17.6677
            9   C1x C    24.7630  -19.6859
            10  O1a O    25.9174  -19.2917
            11  O2x O    21.7357  -17.0300
            12  C5x C    22.4433  -19.6975
            13  C8y C    22.4201  -14.3156
            14  C1x C    25.9174  -16.3278
            15  C8x C    24.7515  -14.3156
            16  N1y N    27.0771  -18.3403
            17  C1x C    23.6090  -20.3645
            18  O5x O    21.2660  -20.3586
            19  C8x C    23.5857  -13.6429
            20  O1a O    21.2486  -13.6429
            21  C1a C    28.4226  -18.3403
            22  C1x C    27.0771  -17.0172
            23  C1x C    24.7979  -16.9886
BOND        26
            1     2   3 1
            2     2   4 1
            3     2   5 1
            4     3   6 1
            5     3   7 2
            6     4   8 1
            7     4   9 1
            8     4  10 1 #Up
            9     5  11 1 #Down
            10    5  12 1
            11    6  13 2
            12    7  14 1
            13    7  15 1
            14    8  16 1 #Up
            15    9  17 1
            16   12  18 2
            17   13  19 1
            18   13  20 1
            19   16  21 1
            20    6  11 1
            21    8  14 1
            22   12  17 1
            23   15  19 2
            24    2  23 1 #Up
            25   23  22 1
            26   16  22 1 #Up