| Entry |
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| Name | Amikacin sulfate (JP18/USP); Amikin (TN) | ||||||||||
| Product | ARIKAYCE (Insmed Incorporated) | ||||||||||
| Generic | AMIKACIN SULFATE (Fresenius Kabi USA), AMIKACIN SULFATE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), AMIKACIN SULFATE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), AMIKACIN SULFATE (Hikma Pharmaceuticals USA), AMIKACIN SULFATE (Sagent Pharmaceuticals), AMIKACIN SULFATE (Teva Parenteral Medicines) | ||||||||||
| Formula | C22H43N5O13. 2H2SO4 | ||||||||||
| Exact mass | 781.2205 | ||||||||||
| Mol weight | 781.7595 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Antibacterial DG01447 Aminoglycoside antibiotic | ||||||||||
| Remark |
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| Efficacy | Antibacterial, Protein biosynthesis inhibitor | ||||||||||
| Target | 30S ribosomal subunit | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] D DERMATOLOGICALS D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE D06A ANTIBIOTICS FOR TOPICAL USE D06AX Other antibiotics for topical use D06AX12 Amikacin D00865 Amikacin sulfate (JP18/USP) <JP/US> J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01G AMINOGLYCOSIDE ANTIBACTERIALS J01GB Other aminoglycosides J01GB06 Amikacin D00865 Amikacin sulfate (JP18/USP) <JP/US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01A ANTIINFECTIVES S01AA Antibiotics S01AA21 Amikacin D00865 Amikacin sulfate (JP18/USP) <JP/US> USP drug classification [BR:br08302] Antibacterials Aminoglycosides Amikacin D00865 Amikacin sulfate (JP18/USP) Therapeutic category of drugs in Japan [BR:br08301] 6 Agents against pathologic organisms and parasites 61 Antibiotics 612 Acting mainly on gram-negative bacteria 6123 Amino sugars D00865 Amikacin sulfate (JP18/USP) 616 Acting mainly on acid-fast bacteria 6169 Others D00865 Amikacin sulfate (JP18/USP) Drug groups [BR:br08330] Antibacterial DG01447 Aminoglycoside antibiotic DG00403 Amikacin D00865 Amikacin sulfate Drug classes [BR:br08332] Antibacterial DG01447 Aminoglycoside antibiotic D00865 Amikacin sulfate Antimicrobials [BR:br08307] Antibacterials Protein biosynthesis inhibitor Aminoglycoside D00865 Amikacin sulfate (JP18/USP) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00865 Amikacin sulfate D00865 Amikacin sulfate injection D00865 Amikacin sulfate for injection New drug approvals in Europe [br08329.html] European public assessment reports (EPAR) authorised medicine D00865 New drug approvals in the USA, Europe and Japan [br08328.html] Approval dates by FDA, EMA and PMDA D00865 Drug groups [BR:br08330] Antibacterial DG01447 Aminoglycoside antibiotic DG00403 Amikacin Antimicrobials abbreviations [BR:br08327] Antibacterials Protein biosynthesis inhibitor Aminoglycoside DG00403 Amikacin | ||||||||||
| Other DBs |
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| KCF data | ATOM 50 1 C1y C 11.5511 -20.1618 2 C1y C 11.5511 -21.5619 3 C1y C 12.7637 -22.2620 4 C1y C 13.9763 -21.5619 5 C1y C 13.9763 -20.1618 6 O2x O 12.7637 -19.4617 7 O2a O 15.2075 -19.4507 8 C1y C 16.3816 -18.7617 9 C1y C 17.5991 -19.4531 10 C1x C 18.8066 -18.7445 11 C1y C 18.7967 -17.3443 12 C1y C 17.5792 -16.6529 13 C1y C 16.3717 -17.3615 14 O2a O 17.5692 -15.2613 15 C1y C 18.7786 -14.5516 16 C1b C 10.3386 -19.4617 17 O1a O 9.1430 -20.1522 18 O1a O 10.3386 -22.2620 19 N1a N 12.7637 -23.6619 20 O1a O 15.2075 -22.2730 21 N1b N 17.5392 -20.8614 22 C5a C 18.7842 -21.5619 23 C1c C 19.9968 -20.8619 24 C1b C 21.2093 -21.5619 25 C1b C 22.4219 -20.8619 26 N1a N 23.6345 -21.5619 27 O2x O 19.9874 -15.2381 28 C1y C 21.1950 -14.5296 29 C1y C 21.1851 -13.1294 30 C1y C 19.9763 -12.4429 31 C1y C 18.7687 -13.1514 32 C1b C 22.4391 -15.2356 33 N1a N 22.4492 -16.6613 34 O1a O 22.3983 -12.4174 35 O1a O 19.9662 -11.0610 36 O1a O 17.5502 -12.4594 37 O5a O 18.7920 -22.9618 38 O1a O 19.9968 -19.4619 39 N1a N 19.9707 -16.6553 40 O1a O 15.1617 -16.6744 41 S4a S 29.6828 -18.0616 42 O1d O 29.6828 -19.4617 43 O1d O 29.6828 -16.6615 44 O1d O 31.0830 -18.0616 45 O1d O 28.2827 -18.0616 46 S4a S 29.6828 -18.0616 47 O1d O 29.6828 -19.4617 48 O1d O 29.6828 -16.6615 49 O1d O 31.0830 -18.0616 50 O1d O 28.2827 -18.0616 BOND 50 1 1 2 1 2 2 3 1 3 3 4 1 4 4 5 1 5 5 6 1 6 1 6 1 7 5 7 1 #Down 8 8 7 1 #Down 9 8 9 1 10 9 10 1 11 10 11 1 12 11 12 1 13 12 13 1 14 8 13 1 15 12 14 1 #Down 16 15 14 1 #Down 17 1 16 1 #Up 18 16 17 1 19 2 18 1 #Down 20 3 19 1 #Up 21 4 20 1 #Down 22 9 21 1 #Up 23 21 22 1 24 22 23 1 25 23 24 1 26 24 25 1 27 25 26 1 28 15 27 1 29 27 28 1 30 28 29 1 31 29 30 1 32 30 31 1 33 15 31 1 34 28 32 1 #Up 35 32 33 1 36 29 34 1 #Down 37 30 35 1 #Up 38 31 36 1 #Down 39 22 37 2 40 23 38 1 #Up 41 11 39 1 #Up 42 13 40 1 #Up 43 41 42 2 44 41 43 2 45 41 44 1 46 41 45 1 47 46 47 2 48 46 48 2 49 46 49 1 50 46 50 1 BRACKET 1 26.8800 -20.0200 26.8800 -15.8900 1 32.5500 -15.8900 32.5500 -20.0200 1 2 ORIGINAL 1 41 42 43 44 45 REPEAT 1 46 47 48 49 50 |