Entry

D00871                      Drug

Name

Sulfacetamide sodium (USP);
Bleph (TN);
Cetamide (TN);
Klaron (TN)

Product

KLARON (Bausch Health US)

Generic

SODIUM SULFACETAMIDE (Oceanside Pharmaceuticals), SULFACETAMIDE SODIUM (A-S Medication Solutions), SULFACETAMIDE SODIUM (Asclemed USA), SULFACETAMIDE SODIUM (Asclemed USA), SULFACETAMIDE SODIUM (Bausch & Lomb Incorporated), SULFACETAMIDE SODIUM (DIRECT RX), SULFACETAMIDE SODIUM (NuCare Pharmaceuticals), SULFACETAMIDE (Pacific Pharma), SULFACETAMIDE SODIUM (Padagis Israel Pharmaceuticals), SULFACETAMIDE SODIUM (Padagis US LLC), SULFACETAMIDE SODIUM (Preferred Pharmaceuticals), SULFACETAMIDE SODIUM (RPK Pharmaceuticals), SULFACETAMIDE SODIUM (Sandoz)

Formula

C8H9N2O3S. Na. H2O

Exact mass

254.0337

Mol weight

254.2387

Structure

Simcomp

Class

Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide

Remark

ATC code:

D10AF06 S01AB04

Chemical structure group:

DG01124

Product (DG01124):

D00871<US>

Product (mixture):

D11699<US>

Efficacy

Antibacterial, Folic acid biosynthesis inhibitor

Disease

Acne vulgaris [DS:H01445]
Trachoma [DS:H00349]

Comment

Sulfonamide

Target

dihydropteroate synthase [KO:K00796]

Pathway

ko00790

Folate biosynthesis

Interaction

Structure map

map07016

Sulfonamide derivatives - sulfa drugs

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AF Antiinfectives for treatment of acne
     D10AF06 Sulfacetamide
      D00871  Sulfacetamide sodium (USP) <US>
S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AB Sulfonamides
     S01AB04 Sulfacetamide
      D00871  Sulfacetamide sodium (USP) <US>
USP drug classification [BR:br08302]
Antibacterials
  Sulfonamides
   Sulfacetamide
    D00871  Sulfacetamide sodium (USP)
Ophthalmic Agents
  Ophthalmic Anti-Infectives
   Antibacterials, Ophthalmic
    Sulfacetamide Sodium
     D00871  Sulfacetamide sodium (USP)
Drug groups [BR:br08330]
Antibacterial
  DG01787  Sulfonamide antibacterial
   DG01784  Short-acting sulfonamide
    DG01124  Sulfacetamide
     D00871  Sulfacetamide sodium
Antimicrobials [BR:br08307]
Antibacterials
  Folic acid biosynthesis inhibitor
   Short-acting sulfonamide
    D00871  Sulfacetamide sodium (USP) <US>
Drug groups [BR:br08330]
Antibacterial
  DG01787  Sulfonamide antibacterial
   DG01784  Short-acting sulfonamide
    DG01124  Sulfacetamide

Other DBs

CAS:

6209-17-2

PubChem:

7847936

ChEBI:

63858

LigandBox:

D00871

NIKKAJI:

J2.207.566G

KCF data

ATOM        16
            1   C8y C    17.9146  -17.3775
            2   S4a S    19.1159  -16.6778
            3   C8x C    17.9146  -18.7828
            4   C8x C    16.7076  -16.6778
            5   N1b N    20.3287  -17.3775 #-
            6   O3c O    20.1071  -15.6808
            7   O3c O    18.1304  -15.6865
            8   C8x C    16.7076  -19.4767
            9   C8x C    15.4889  -17.3775
            10  C5a C    21.5416  -16.6778
            11  C8y C    15.4889  -18.7828
            12  C1a C    22.7485  -17.3775
            13  O5a O    21.5300  -15.2726
            14  N1a N    14.2701  -19.4708
            15  Z   Na   24.4628  -15.5991 #+
            16  O0  O    28.1169  -16.9868
BOND        14
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     2   6 2
            6     2   7 2
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    8  11 1
            11   10  12 1
            12   10  13 2
            13   11  14 1
            14    9  11 2