Rimantadine hydrochloride

Entry

D00901                      Drug

Name

Rimantadine hydrochloride (USP);
Flumadine (TN)

Product

Generic

RIMANTADINE HYDROCHLORIDE (Amneal Pharmaceuticals of New York LLC), RIMANTADINE HYDROCHLORIDE (Bryant Ranch Prepack)

Formula

C12H21N. HCl

Exact mass

215.1441

Mol weight

215.7628

Structure

Simcomp

Class

Antiviral
DG03029 Anti-influenza virus agent
DG02841 Viral uncoating inhibitor

Remark

Same as:

C08094

ATC code:

J05AC02

Chemical structure group:

DG00650

Product (DG00650):

D00901<US>

Efficacy

Antiviral, M2 protein inhibitor

Disease

Influenza A virus [DS:H00398]

Comment

Adamantane derivative

Target

Influenza A virus M2 [KO:K19394]

Pathway

ko03230

Viral genome structure

ko05164

Influenza A

Structure map

map07044

Antiviral agents

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AC Cyclic amines
     J05AC02 Rimantadine
      D00901  Rimantadine hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Antivirals
  Anti-influenza Agents
   Rimantadine
    D00901  Rimantadine hydrochloride (USP)
Drug groups [BR:br08330]
Antiviral
  DG03029  Anti-influenza virus agent
   DG02841  Viral uncoating inhibitor
    DG00650  Rimantadine
     D00901  Rimantadine hydrochloride
Drug classes [BR:br08332]
Antiviral
  DG03029  Anti-influenza virus agent
   D00901  Rimantadine hydrochloride
Antimicrobials [BR:br08307]
Antivirals
  Entry, fusion or uncoating inhibitor
   Influenza virus uncoating inhibitor
    D00901  Rimantadine hydrochloride (USP) <US>
Drug groups [BR:br08330]
Antiviral
  DG03029  Anti-influenza virus agent
   DG02841  Viral uncoating inhibitor
    DG00650  Rimantadine
Antimicrobials abbreviations [BR:br08327]
Antivirals
  Entry, fusion or uncoating inhibitor
   Influenza virus uncoating inhibitor
    DG00650  Rimantadine

Other DBs

CAS:

1501-84-4

PubChem:

7847965

ChEBI:

8865

LigandBox:

D00901

NIKKAJI:

J394.697E

KCF data

ATOM        14
            1   C1z C    24.9898  -18.0809
            2   C1c C    24.9957  -16.8409
            3   C1x C    24.3641  -19.5663
            4   C1x C    23.9253  -18.6891
            5   C1x C    26.0542  -18.6891
            6   C1a C    23.9313  -16.2210
            7   N1a N    26.0719  -16.2327
            8   C1y C    24.3641  -20.7069
            9   C1y C    23.9253  -19.9114
            10  C1y C    26.0542  -19.9114
            11  C1x C    22.6212  -21.1806
            12  C1x C    25.5396  -21.7946
            13  C1x C    24.9898  -20.5313
            14  X   Cl   29.0018  -18.2211
BOND        15
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    8  11 1
            11    8  12 1
            12    9  13 1
            13    9  11 1
            14   10  12 1
            15   10  13 1