| Entry |
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| Name | Cefuroxime axetil (JP18/USP/INN); Ceftin (TN) | ||||||||||
| Product | |||||||||||
| Generic | CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (A-S Medication Solutions), CEFUROXIME AXETIL (American Health Packaging), CEFUROXIME AXETIL (Ascend Laboratories), CEFUROXIME AXETIL (Aurobindo Pharma Limited), CEFUROXIME AXETIL (DIRECT RX), CEFUROXIME AXETIL (Denton Pharma), CEFUROXIME AXETIL (Direct_Rx), CEFUROXIME AXETIL (Golden State Medical Supply), CEFUROXIME AXETIL (Golden State Medical Supply), CEFUROXIME AXETIL (Lupin Pharmaceuticals), CEFUROXIME AXETIL (NorthStar Rx LLC), CEFUROXIME AXETIL (NuCare Pharmaceuticals), CEFUROXIME AXETIL (NuCare Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (PD-Rx Pharmaceuticals), CEFUROXIME AXETIL (Proficient Rx LP), CEFUROXIME AXETIL (REMEDYREPACK), CEFUROXIME AXETIL (REMEDYREPACK), CEFUROXIME AXETIL (RPK Pharmaceuticals), CEFUROXIME AXETIL (RPK Pharmaceuticals), CEFUROXIME AXETIL (Rising Health), CEFUROXIME AXETIL (Wockhardt USA LLC.) | ||||||||||
| Formula | C20H22N4O10S | ||||||||||
| Exact mass | 510.1057 | ||||||||||
| Mol weight | 510.4745 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Antibacterial DG01710 beta-Lactam antibiotic DG01714 Cephalosporin skeleton group DG01488 Cephem DG01775 Second-generation cephalosporin DG01804 Oxyimino beta-lactam | ||||||||||
| Remark |
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| Efficacy | Antibacterial, Cell wall biosynthesis inhibitor | ||||||||||
| Disease | Uncomplicated urinary tract infections [DS:H01176] Gonorrhea [DS:H00315] Lyme disease [DS:H00353] | ||||||||||
| Comment | Active form of prodrug: Cefuroxime [DR:D00262] | ||||||||||
| Target | penicillin binding protein | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01D OTHER BETA-LACTAM ANTIBACTERIALS J01DC Second-generation cephalosporins J01DC02 Cefuroxime D00914 Cefuroxime axetil (JP18/USP/INN) <JP/US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01A ANTIINFECTIVES S01AA Antibiotics S01AA27 Cefuroxime D00914 Cefuroxime axetil (JP18/USP/INN) <JP/US> USP drug classification [BR:br08302] Antibacterials Beta-lactam, Cephalosporins Cefuroxime D00914 Cefuroxime axetil (JP18/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 6 Agents against pathologic organisms and parasites 61 Antibiotics 613 Acting mainly on gram-positive and gram-negative bacteria 6132 Cephem antibioitics D00914 Cefuroxime axetil (JP18/USP/INN) Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01714 Cephalosporin skeleton group DG01488 Cephem DG00558 Cefuroxime D00914 Cefuroxime axetil DG01775 Second-generation cephalosporin DG00558 Cefuroxime D00914 Cefuroxime axetil DG01804 Oxyimino beta-lactam DG00558 Cefuroxime D00914 Cefuroxime axetil Drug classes [BR:br08332] Antibacterial DG01488 Cephem D00914 Cefuroxime axetil Antimicrobials [BR:br08307] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam Second-generation cephalosporin D00914 Cefuroxime axetil (JP18/USP/INN) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00914 Cefuroxime axetil Prodrugs [br08324.html] D00914 Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01714 Cephalosporin skeleton group DG01488 Cephem DG00558 Cefuroxime DG01775 Second-generation cephalosporin DG00558 Cefuroxime DG01804 Oxyimino beta-lactam DG00558 Cefuroxime Antimicrobials abbreviations [BR:br08327] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam Second-generation cephalosporin DG00558 Cefuroxime | ||||||||||
| Other DBs |
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| KCF data | ATOM 35 1 C1y C 32.4830 -17.3815 2 N1y N 32.4830 -18.7522 3 C2y C 33.6704 -19.4375 4 C2y C 34.8574 -18.7522 5 C1x C 34.8574 -17.3815 6 S2x S 33.6704 -16.6961 7 C1y C 31.1122 -17.3815 8 C5x C 31.1122 -18.7522 9 N1b N 29.9252 -16.6961 10 C5a C 28.7380 -17.3815 11 O5a O 28.7380 -18.7522 12 O5x O 29.9252 -19.4375 13 C2c C 27.5508 -16.6961 14 C1b C 36.0626 -19.4485 15 C7a C 33.6704 -21.8391 16 O7a O 32.4665 -22.5342 17 O6a O 34.8407 -22.5150 18 C8y C 26.3447 -17.3929 19 O2x O 25.2137 -16.5965 20 C8x C 24.1023 -17.4263 21 C8x C 24.5479 -18.7397 22 C8x C 25.9347 -18.7220 23 N2b N 27.5507 -15.3044 24 O7a O 37.2666 -18.7539 25 C7a C 38.4302 -19.4263 26 N1a N 39.6019 -18.7501 27 O6a O 38.4298 -20.8040 28 C1c C 31.2867 -21.8527 29 O7a O 30.1305 -22.5200 30 C7a C 28.9560 -21.8415 31 C1a C 27.7902 -22.5142 32 C1a C 31.2864 -20.4575 33 O6a O 28.9562 -20.4574 34 O2a O 28.7734 -14.5979 35 C1a C 28.7734 -13.1979 BOND 37 1 1 2 1 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 1 6 1 6 1 7 1 7 1 8 7 8 1 9 2 8 1 10 7 9 1 #Up 11 9 10 1 12 10 11 2 13 8 12 2 14 10 13 1 15 4 14 1 16 3 15 1 17 15 16 1 18 15 17 2 19 13 18 1 20 18 19 1 21 19 20 1 22 20 21 2 23 21 22 1 24 18 22 2 25 13 23 2 26 14 24 1 27 24 25 1 28 25 26 1 29 25 27 2 30 16 28 1 31 28 29 1 32 29 30 1 33 30 31 1 34 28 32 1 35 30 33 2 36 23 34 1 37 34 35 1 |