| Entry |
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| Name | Cefuroxime sodium (JAN/USP); Zinacef (TN) | ||||||||||
| Product | |||||||||||
| Generic | CEFUROXIME (Hikma Pharmaceuticals USA), CEFUROXIME (Hikma Pharmaceuticals USA), CEFUROXIME (Hikma Pharmaceuticals USA), CEFUROXIME (Hikma Pharmaceuticals USA), CEFUROXIME SODIUM (Sagent Pharmaceuticals), CEFUROXIME SODIUM (Sagent Pharmaceuticals) | ||||||||||
| Formula | C16H15N4O8S. Na | ||||||||||
| Exact mass | 446.0508 | ||||||||||
| Mol weight | 446.3671 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Antibacterial DG01710 beta-Lactam antibiotic DG01714 Cephalosporin skeleton group DG01488 Cephem DG01775 Second-generation cephalosporin DG01804 Oxyimino beta-lactam | ||||||||||
| Remark |
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| Efficacy | Antibacterial, Cell wall biosynthesis inhibitor | ||||||||||
| Disease | Gonorrhea [DS:H00315] | ||||||||||
| Target | penicillin binding protein | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01D OTHER BETA-LACTAM ANTIBACTERIALS J01DC Second-generation cephalosporins J01DC02 Cefuroxime D00915 Cefuroxime sodium (JAN/USP) <US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01A ANTIINFECTIVES S01AA Antibiotics S01AA27 Cefuroxime D00915 Cefuroxime sodium (JAN/USP) <US> USP drug classification [BR:br08302] Antibacterials Beta-lactam, Cephalosporins Cefuroxime D00915 Cefuroxime sodium (JAN/USP) Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01714 Cephalosporin skeleton group DG01488 Cephem DG00558 Cefuroxime D00915 Cefuroxime sodium DG01775 Second-generation cephalosporin DG00558 Cefuroxime D00915 Cefuroxime sodium DG01804 Oxyimino beta-lactam DG00558 Cefuroxime D00915 Cefuroxime sodium Drug classes [BR:br08332] Antibacterial DG01488 Cephem D00915 Cefuroxime sodium Antimicrobials [BR:br08307] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam Second-generation cephalosporin D00915 Cefuroxime sodium (JAN/USP) <US> Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01714 Cephalosporin skeleton group DG01488 Cephem DG00558 Cefuroxime DG01775 Second-generation cephalosporin DG00558 Cefuroxime DG01804 Oxyimino beta-lactam DG00558 Cefuroxime Antimicrobials abbreviations [BR:br08327] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam Second-generation cephalosporin DG00558 Cefuroxime | ||||||||||
| Other DBs |
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| KCF data | ATOM 30 1 C1y C 32.5439 -17.8678 2 N1y N 32.5439 -19.2637 3 C2y C 33.7531 -19.9616 4 C2y C 34.9620 -19.2637 5 C1x C 34.9620 -17.8678 6 S2x S 33.7531 -17.1697 7 C1y C 31.1478 -17.8678 8 C5x C 31.1478 -19.2637 9 N1b N 29.9390 -17.1697 10 C5a C 28.7299 -17.8678 11 O5a O 28.7299 -19.2637 12 O5x O 29.9390 -19.9616 13 C2c C 27.5208 -17.1697 14 C1b C 36.1894 -19.9728 15 C6a C 33.7531 -21.3574 16 O6a O 32.5271 -22.0653 17 O6a O 34.9450 -22.0458 #- 18 C8y C 26.2925 -17.8794 19 O2x O 25.1407 -17.0683 20 C8x C 24.0088 -17.9134 21 C8x C 24.4626 -19.2510 22 C8x C 25.8750 -19.2329 23 N2b N 27.5207 -15.7524 24 O7a O 37.4156 -19.2654 25 C7a C 38.6006 -19.9502 26 N1a N 39.7939 -19.2616 27 O6a O 38.6002 -21.3533 28 O2a O 28.7261 -15.0563 29 C1a C 28.7261 -13.6563 30 Z Na 36.2600 -21.9800 #+ BOND 31 1 1 2 1 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 1 6 1 6 1 7 1 7 1 8 7 8 1 9 2 8 1 10 7 9 1 #Up 11 9 10 1 12 10 11 2 13 8 12 2 14 10 13 1 15 4 14 1 16 3 15 1 17 15 16 2 18 15 17 1 19 13 18 1 20 18 19 1 21 19 20 1 22 20 21 2 23 21 22 1 24 18 22 2 25 13 23 2 26 14 24 1 27 24 25 1 28 25 26 1 29 25 27 2 30 23 28 1 31 28 29 1 |