| Entry |
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|---|---|---|---|---|---|---|---|---|---|
| Name | Nafcillin sodium (USP); Nafcillin sodium monohydrate; Unipen (TN) | ||||||||
| Product | NAFCILLIN (Baxter Healthcare Corporation) | ||||||||
| Generic | NAFCILLIN (Fresenius Kabi USA), NAFCILLIN (Sandoz), NAFCILLIN (Sandoz), NAFCILLIN (Sandoz), NAFCILLIN (Sandoz), NAFCILLIN (WG Critical Care), NAFCILLIN (WG Critical Care), NAFCILLIN (Methapharm), NAFCILLIN (Athenex Pharmaceutical Division), NAFCILLIN (Athenex Pharmaceutical Division), NAFCILLIN (AuroMedics Pharma LLC), NAFCILLIN (AuroMedics Pharma LLC), NAFCILLIN (AuroMedics Pharma LLC), NAFCILLIN (AuroMedics Pharma LLC), NAFCILLIN (Fresenius Kabi USA), NAFCILLIN (Fresenius Kabi USA), NAFCILLIN (Sagent Pharmaceuticals), NAFCILLIN (Sagent Pharmaceuticals), NAFCILLIN SODIUM (Sandoz), NAFCILLIN SODIUM (Sandoz) | ||||||||
| Formula | C21H21N2O5S. Na. H2O | ||||||||
| Exact mass | 454.1175 | ||||||||
| Mol weight | 454.4719 | ||||||||
| Structure |  | ||||||||
| Simcomp | |||||||||
| Class | Antibacterial DG01710 beta-Lactam antibiotic DG01713 Penicillin skeleton group DG01480 Penicillin DG01779 beta-Lactamase resistant penicillin | ||||||||
| Remark |
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| Efficacy | Antibacterial, Cell wall biosynthesis inhibitor | ||||||||
| Target | penicillin binding protein | ||||||||
| Pathway |
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| Interaction | |||||||||
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS J01CF Beta-lactamase resistant penicillins J01CF06 Nafcillin D00928 Nafcillin sodium (USP) <US> USP drug classification [BR:br08302] Antibacterials Beta-lactam, Penicillins Nafcillin D00928 Nafcillin sodium (USP) Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01713 Penicillin skeleton group DG01480 Penicillin DG00544 Nafcillin D00928 Nafcillin sodium DG01779 beta-Lactamase resistant penicillin DG00544 Nafcillin D00928 Nafcillin sodium Drug classes [BR:br08332] Antibacterial DG01480 Penicillin D00928 Nafcillin sodium Antimicrobials [BR:br08307] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam beta-Lactamase resistant penicillin D00928 Nafcillin sodium (USP) <US> Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01713 Penicillin skeleton group DG01480 Penicillin DG00544 Nafcillin DG01779 beta-Lactamase resistant penicillin DG00544 Nafcillin Antimicrobials abbreviations [BR:br08327] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam beta-Lactamase resistant penicillin DG00544 Nafcillin | ||||||||
| Other DBs |
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| KCF data | ATOM 31 1 C1y C 12.9493 -12.7967 2 C5x C 12.9493 -14.1867 3 N1y N 14.3393 -14.1867 4 C1y C 14.3393 -12.7967 5 C1y C 15.6598 -14.6036 6 C1z C 16.4938 -13.4916 7 S2x S 15.6598 -12.3797 8 C1a C 17.4668 -14.4647 9 C1a C 17.4668 -12.5187 10 C6a C 16.1463 -15.9937 11 O6a O 17.5362 -15.9937 #- 12 O6a O 15.3123 -17.1057 13 N1b N 11.7679 -12.1017 14 C5a C 10.5863 -12.7967 15 O5x O 11.7679 -14.8817 16 O5a O 10.5863 -14.1867 17 C8y C 9.3354 -12.1017 18 C8y C 9.3354 -10.7118 19 C8x C 8.1229 -10.0118 20 C8x C 6.9105 -10.7118 21 C8y C 6.9105 -12.1017 22 C8y C 8.1229 -12.8017 23 C8x C 5.6981 -12.8017 24 C8x C 5.6981 -14.2017 25 C8x C 6.9105 -14.9017 26 C8x C 8.1229 -14.2017 27 O2a O 10.5294 -10.0222 28 C1b C 10.5294 -8.6222 29 C1a C 11.7247 -7.9316 30 Z Na 19.1347 -16.0631 #+ 31 O0 O 22.5627 -13.7401 BOND 32 1 1 2 1 2 2 3 1 3 3 4 1 4 1 4 1 5 3 5 1 6 5 6 1 7 6 7 1 8 4 7 1 9 6 8 1 10 6 9 1 11 5 10 1 #Down 12 10 11 1 13 10 12 2 14 1 13 1 #Up 15 13 14 1 16 2 15 2 17 14 16 2 18 14 17 1 19 17 18 1 20 18 19 2 21 19 20 1 22 20 21 2 23 21 22 1 24 17 22 2 25 21 23 1 26 23 24 2 27 24 25 1 28 25 26 2 29 22 26 1 30 18 27 1 31 27 28 1 32 28 29 1 |