Entry

D01000                      Drug

Name

Bethanechol chloride (JP18/USP);
Urecholine (TN)

Product

Generic

BETHANECHOL CHLORIDE (American Health Packaging), BETHANECHOL CHLORIDE (American Health Packaging), BETHANECHOL CHLORIDE (Amneal Pharmaceuticals LLC), BETHANECHOL CHLORIDE (Amneal Pharmaceuticals of New York LLC), BETHANECHOL CHLORIDE (Bryant Ranch Prepack), BETHANECHOL CHLORIDE (Bryant Ranch Prepack), BETHANECHOL CHLORIDE (Bryant Ranch Prepack), BETHANECHOL CHLORIDE (Bryant Ranch Prepack), BETHANECHOL CHLORIDE (Bryant Ranch Prepack), BETHANECHOL CHLORIDE (Bryant Ranch Prepack), BETHANECHOL CHLORIDE (ECI Pharmaceuticals LLC), BETHANECHOL CHLORIDE (Lannett Company), BETHANECHOL CHLORIDE (Major Pharmaceuticals), BETHANECHOL CHLORIDE (Upsher-Smith Laboratories)

Formula

C7H17N2O2. Cl

Exact mass

196.0979

Mol weight

196.6751

Structure

Simcomp

Class

Neuropsychiatric agent
DG01490 Muscarinic cholinergic receptor agonist
DG01719 Parasympathomimetic agent

Remark

Same as:

C08202

Therapeutic category:

1231

ATC code:

N07AB02

Chemical structure group:

DG00991

Product (DG00991):

D01000<JP/US>

Efficacy

Prokinetic, Muscarinic acetylcholine receptor agonist

Comment

Quaternary ammonium compound

Target

CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]

Pathway

hsa04080

Neuroactive ligand-receptor interaction

hsa04725

Cholinergic synapse

hsa04971

Gastric acid secretion

Interaction

Structure map

map07220

Cholinergic and anticholinergic drugs

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07A PARASYMPATHOMIMETICS
    N07AB Choline esters
     N07AB02 Bethanechol
      D01000  Bethanechol chloride (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Genitourinary Agents
  Genitourinary Agents, Other
   Bethanechol
    D01000  Bethanechol chloride (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   123  Autonomic nervous system agents
    1231  Quaternary ammoniums
     D01000  Bethanechol chloride (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
  Inorganic and organic chemicals
   Bethanechol
    D01000  Bethanechol chloride (JP18/USP)
Second-class OTC drugs
  Inorganic and organic chemicals
   Bethanechol chloride
    D01000  Bethanechol chloride (JP18/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG01490  Muscarinic cholinergic receptor agonist
   DG00991  Bethanechol
    D01000  Bethanechol chloride
  DG01719  Parasympathomimetic agent
   DG00991  Bethanechol
    D01000  Bethanechol chloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D01000  Bethanechol chloride (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D01000  Bethanechol chloride
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG01490  Muscarinic cholinergic receptor agonist
   DG00991  Bethanechol
  DG01719  Parasympathomimetic agent
   DG00991  Bethanechol

Other DBs

CAS:

590-63-6

PubChem:

7848063

ChEBI:

3085

LigandBox:

D01000

NIKKAJI:

J277.869F

KCF data

ATOM        12
            1   N1d N    20.0900  -17.0100 #+
            2   C1b C    21.2100  -17.6400
            3   C1a C    19.3200  -15.5400
            4   C1a C    18.6200  -17.0100
            5   C1a C    19.3200  -18.4100
            6   C1c C    22.3300  -17.0100
            7   O7a O    23.5200  -17.6400
            8   C7a C    24.6400  -17.0100
            9   N1a N    25.7600  -17.6400
            10  O6a O    24.6400  -15.6800
            11  C1a C    22.3122  -15.6101
            12  X   Cl   29.1900  -17.2900 #-
BOND        10
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     6   7 1
            7     7   8 1
            8     8   9 1
            9     8  10 2
            10    6  11 1