| Entry |
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| Name | Gentamicin sulfate (JP18/USP); Garamycin (TN); Gentacin (TN) | ||||||||||||
| Product | |||||||||||||
| Generic | GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (HF Acquisition Co LLC), GENTAMICIN (Hikma Pharmaceuticals USA), GENTAMICIN SULFATE (A-S Medication Solutions), GENTAK (A-S Medication Solutions), GENTAMICIN SULFATE (Akorn), GENTAK (Akorn), GENTAMICIN SULFATE (Asclemed USA), GENTAMICIN SULFATE (Asclemed USA), GENTAMICIN SULFATE (Bausch & Lomb Incorporated), GENTAMICIN SULFATE IN SODIUM CHLORIDE (Baxter Healthcare Corporation), GENTAMICIN SULFATE (Cardinal Health), GENTAMICIN SULFATE (Cosette Pharmaceuticals), GENTAMICIN SULFATE (Cosette Pharmaceuticals), GENTAMICIN SULFATE (DIRECT RX), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN SULFATE (General Injectables & Vaccines), GENTAMICIN (General Injectables & Vaccines), GENTAMICIN (Henry Schein), GENTAMICIN SULFATE (Henry Schein), GENTAMICIN SULFATE (Hospira), GENTAMICIN SULFATE (Hospira), GENTAMICIN SULFATE (Medical Purchasing Solutions), GENTAMICIN SULFATE (Medsource Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAK (NuCare Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAMICIN SULFATE (Pacific Pharma), GENTAMICIN SULFATE (Padagis Israel Pharmaceuticals), GENTAMICIN SULFATE (Padagis Israel Pharmaceuticals), GENTAMICIN SULFATE (Preferred Pharmaceuticals), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAK (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (REMEDYREPACK), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (Sandoz), GENTAMICIN SULFATE (Teligent Pharma), GENTAMICIN SULFATE OPTH SOLUTION (Direct_Rx) | ||||||||||||
| Formula | C19H37N5O7(R1)(R2). H2SO4 | ||||||||||||
| Structure |  | ||||||||||||
| Simcomp | |||||||||||||
| Source | Micromonospora purpurea [TAX:1877] | ||||||||||||
| Class | Antibacterial DG01447 Aminoglycoside antibiotic | ||||||||||||
| Remark |
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| Efficacy | Antibacterial, Protein biosynthesis inhibitor | ||||||||||||
| Disease | Bacterial endocarditis [DS:H00334] | ||||||||||||
| Comment | R1,R2: See Gentamicin C [CPD:C01918] | ||||||||||||
| Target | 30S ribosomal subunit | ||||||||||||
| Pathway |
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| Interaction | |||||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] D DERMATOLOGICALS D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE D06A ANTIBIOTICS FOR TOPICAL USE D06AX Other antibiotics for topical use D06AX07 Gentamicin D01063 Gentamicin sulfate (JP18/USP) <JP/US> J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01G AMINOGLYCOSIDE ANTIBACTERIALS J01GB Other aminoglycosides J01GB03 Gentamicin D01063 Gentamicin sulfate (JP18/USP) <JP/US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01A ANTIINFECTIVES S01AA Antibiotics S01AA11 Gentamicin D01063 Gentamicin sulfate (JP18/USP) <JP/US> S02 OTOLOGICALS S02A ANTIINFECTIVES S02AA Antiinfectives S02AA14 Gentamicin D01063 Gentamicin sulfate (JP18/USP) <JP/US> S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS S03A ANTIINFECTIVES S03AA Antiinfectives S03AA06 Gentamicin D01063 Gentamicin sulfate (JP18/USP) <JP/US> USP drug classification [BR:br08302] Antibacterials Aminoglycosides Gentamicin D01063 Gentamicin sulfate (JP18/USP) Dermatological Agents Topical Anti-infectives Antibacterials, dermatological Gentamicin D01063 Gentamicin sulfate (JP18/USP) Ophthalmic Agents Ophthalmic Anti-Infectives Antibacterials, Ophthalmic Gentamicin D01063 Gentamicin sulfate (JP18/USP) Therapeutic category of drugs in Japan [BR:br08301] 1 Agents affecting nervous system and sensory organs 13 Agents affecting sensory organs 131 Ophthalmic agents 1317 Ophthalmic antibiotics D01063 Gentamicin sulfate (JP18/USP) 2 Agents affecting individual organs 26 Epidermides 263 Suppurative dermatosis agents 2634 Antibiotics for external use D01063 Gentamicin sulfate (JP18/USP) 6 Agents against pathologic organisms and parasites 61 Antibiotics 613 Acting mainly on gram-positive and gram-negative bacteria 6134 Amino sugars D01063 Gentamicin sulfate (JP18/USP) Drug groups [BR:br08330] Antibacterial DG01447 Aminoglycoside antibiotic DG00401 Gentamicin D01063 Gentamicin sulfate Drug classes [BR:br08332] Antibacterial DG01447 Aminoglycoside antibiotic D01063 Gentamicin sulfate Antimicrobials [BR:br08307] Antibacterials Protein biosynthesis inhibitor Aminoglycoside D01063 Gentamicin sulfate (JP18/USP) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D01063 Gentamicin sulfate D01063 Gentamicin sulfate injection D01063 Gentamicin sulfate ophthalmic solution D01063 Gentamicin sulfate ointment Drug groups [BR:br08330] Antibacterial DG01447 Aminoglycoside antibiotic DG00401 Gentamicin Antimicrobials abbreviations [BR:br08327] Antibacterials Protein biosynthesis inhibitor Aminoglycoside DG00401 Gentamicin | ||||||||||||
| Other DBs |
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| KCF data | ATOM 38 1 S4a S 53.5166 -22.8214 2 O1d O 53.5166 -21.4177 3 O1d O 53.5166 -24.1551 4 O1d O 54.9203 -22.8214 5 O1d O 52.1830 -22.8214 6 C1x C 38.9466 -19.9619 7 C1z C 38.9466 -21.3632 8 C1y C 40.1600 -22.0639 9 C1y C 41.3736 -21.3632 10 C1y C 41.3736 -19.9619 11 O2x O 40.1600 -19.2614 12 O2a O 42.6058 -19.2504 13 C1y C 43.8193 -18.5497 14 C1y C 45.0612 -19.2669 15 C1x C 46.2748 -18.5664 16 C1y C 46.2750 -17.1651 17 C1y C 45.0331 -16.4480 18 C1y C 43.8195 -17.1484 19 O1a O 42.6058 -22.0749 20 C1a C 38.5840 -22.7167 21 O1a O 37.5453 -21.3632 22 N1b N 40.1600 -23.4649 23 C1a C 38.9298 -24.1754 24 N1a N 45.0610 -20.6625 25 O1a O 42.6345 -16.4639 26 N1a N 47.5120 -16.4509 27 O2a O 45.0333 -15.0576 28 C1y C 46.2535 -14.3534 29 O2x O 47.4531 -15.0464 30 C1y C 48.6668 -14.3461 31 C1x C 48.6671 -12.9449 32 C1x C 47.4675 -12.2519 33 C1y C 46.2538 -12.9521 34 C1c C 49.8987 -15.0577 35 Z R# 51.0955 -14.3670 36 N1b N 49.8984 -16.4586 37 Z R# 51.0952 -17.1500 38 N1a N 45.0266 -12.2431 BOND 39 1 1 2 2 2 1 3 2 3 1 4 1 4 1 5 1 5 6 7 1 6 7 8 1 7 8 9 1 8 9 10 1 9 10 11 1 10 6 11 1 11 10 12 1 #Down 12 13 12 1 #Down 13 13 14 1 14 14 15 1 15 15 16 1 16 16 17 1 17 17 18 1 18 13 18 1 19 9 19 1 #Down 20 7 20 1 #Down 21 7 21 1 #Up 22 8 22 1 #Up 23 22 23 1 24 14 24 1 #Up 25 18 25 1 #Up 26 16 26 1 #Up 27 17 27 1 #Down 28 28 27 1 #Down 29 28 29 1 30 29 30 1 31 30 31 1 32 31 32 1 33 32 33 1 34 28 33 1 35 30 34 1 36 34 35 1 #Up 37 34 36 1 38 36 37 1 39 33 38 1 #Down |