Entry |
|
Name |
Piperidolate hydrochloride (JAN); Dactil (TN) |
Formula |
C21H25NO2. HCl
|
Exact mass |
359.1652
|
Mol weight |
359.8896
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
Remark |
Therapeutic category: | 1249 |
Chemical structure group: | DG00034 |
Product (DG00034): | D01165<JP> |
|
Efficacy |
Antispasmodic, Muscarinic acetylcholine receptor antagonist |
Target |
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133] |
Pathway |
hsa04020 | Calcium signaling pathway |
hsa04024 | cAMP signaling pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
hsa04725 | Cholinergic synapse |
hsa04970 | Salivary secretion |
hsa04971 | Gastric acid secretion |
hsa04972 | Pancreatic secretion |
|
Interaction |
|
Structure map |
map07220 | Cholinergic and anticholinergic drugs |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03AA Synthetic anticholinergics, esters with tertiary amino group
A03AA30 Piperidolate
D01165 Piperidolate hydrochloride (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
12 Agents affecting peripheral nervous system
124 Antispasmodics
1249 Others
D01165 Piperidolate hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00034 Piperidolate
D01165 Piperidolate hydrochloride
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00034 Piperidolate
D01165 Piperidolate hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D01165 Piperidolate hydrochloride (JAN) <JP>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00034 Piperidolate
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG00034 Piperidolate
|
Other DBs |
|
KCF data |
ATOM 25
1 C8x C 28.0660 -21.8349
2 C8x C 29.2704 -21.1216
3 C8x C 29.2535 -19.7194
4 C8x C 28.0357 -19.0366
5 C8y C 26.8313 -19.7498
6 C8x C 26.8446 -21.1459
7 C1c C 25.6119 -19.0624
8 C8y C 25.5975 -17.6628
9 C7a C 24.4069 -19.7747
10 O7a O 23.1874 -19.0874
11 O6a O 24.4214 -21.1746
12 C8x C 26.8035 -16.9561
13 C8x C 26.7891 -15.5565
14 C8x C 25.5697 -14.8693
15 C8x C 24.3647 -15.5815
16 C8x C 24.3793 -16.9812
17 C1y C 21.9594 -19.8132
18 C1x C 20.7542 -19.1336
19 N1y N 19.5490 -19.8458
20 C1x C 19.5631 -21.2458
21 C1x C 20.7683 -21.9254
22 C1x C 21.9736 -21.2132
23 C1b C 18.3302 -19.1586
24 C1a C 17.1230 -19.8720
25 X Cl 30.8735 -20.9800
BOND 26
1 5 6 2
2 6 1 1
3 5 7 1
4 8 12 2
5 12 13 1
6 13 14 2
7 14 15 1
8 15 16 2
9 16 8 1
10 7 8 1
11 1 2 2
12 7 9 1
13 2 3 1
14 9 10 1
15 3 4 2
16 9 11 2
17 4 5 1
18 10 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 20 21 1
23 21 22 1
24 17 22 1
25 19 23 1
26 23 24 1
|