Mafenide acetate


Entry
D01166                      Drug                                   
Name
Mafenide acetate (JAN/USP);
Sulfamylon (TN)
Product
SULFAMYLON (Mylan Institutional), SULFAMYLON (Mylan Institutional), SULFAMYLON (Rising Pharma Holdings)
  Generic
MAFENIDE ACETATE (Ingenus Pharmaceuticals), MAFENIDE ACETATE (Par Pharmaceutical)
Formula
C7H10N2O2S. C2H4O2
Exact mass
246.0674
Mol weight
246.2835
Structure
Simcomp
Class
Antibacterial
 DG01787  Sulfonamide antibacterial
Remark
ATC code: D06BA03
Chemical structure group: DG00404
Product (DG00404): D01166<US>
Efficacy
Antibacterial (topical)
Comment
Sulfonamide
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
    D06BA Sulfonamides
     D06BA03 Mafenide
      D01166  Mafenide acetate (JAN/USP) <US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Topical Anti-infectives
   Antibacterials, dermatological
    Mafenide
     D01166  Mafenide acetate (JAN/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01787  Sulfonamide antibacterial
   DG00404  Mafenide
    D01166  Mafenide acetate
Antimicrobials [BR:br08307]
 Antibacterials
  Folic acid biosynthesis inhibitor
   Other sulfonamide
    D01166  Mafenide acetate (JAN/USP) <US>
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D01166
Drug groups [BR:br08330]
 Antibacterial
  DG01787  Sulfonamide antibacterial
   DG00404  Mafenide
Other DBs
CAS: 13009-99-9
PubChem: 7848229
ChEBI: 31792
LigandBox: D01166
NIKKAJI: J320.977F
KCF data

ATOM        16
            1   C8y C    17.0100  -16.1700
            2   C8x C    15.8200  -15.4700
            3   C8x C    17.0100  -17.5000
            4   S4a S    18.1300  -15.4700
            5   C8x C    14.7000  -16.1000
            6   C8x C    15.8200  -18.1300
            7   O3c O    17.3600  -14.2100
            8   O3c O    19.4600  -14.7000
            9   N1a N    18.9700  -16.9400
            10  C8y C    14.7000  -17.5000
            11  C1b C    13.5100  -18.1300
            12  N1a N    12.3200  -17.5000
            13  C6a C    23.6600  -16.3800
            14  C1a C    24.9200  -17.0800
            15  O6a O    22.4700  -17.0800
            16  O6a O    23.6600  -14.9800
BOND        15
            1     1   4 1
            2     2   5 1
            3     3   6 2
            4     4   7 2
            5     4   8 2
            6     4   9 1
            7     5  10 2
            8    10  11 1
            9    11  12 1
            10    6  10 1
            11    1   2 2
            12    1   3 1
            13   13  14 1
            14   13  15 1
            15   13  16 2