Tocopherol nicotinate


Entry
D01530                      Drug                                   
Name
Tocopherol nicotinate (JP18);
dl-alpha-Tocopherol nicotinate;
Juvela nicotinate (TN)
Formula
C35H53NO3
Exact mass
535.4025
Mol weight
535.8002
Structure
Simcomp
Class
Hypolipidemic agent
 DG01946  Hypolipidemic agent
Remark
Same as: C12981
Therapeutic category: 2190
ATC code: A11HA03
Chemical structure group: DG00129
Product (DG00129): D01530<JP> D01735<JP>
Efficacy
Microcirculation sysutem activator, Supplement (vitamin E)
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A11 VITAMINS
   A11H OTHER PLAIN VITAMIN PREPARATIONS
    A11HA Other plain vitamin preparations
     A11HA03 Tocopherol (vit E)
      D01530  Tocopherol nicotinate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   219  Miscellaneous
    2190  Miscellaneous
     D01530  Tocopherol nicotinate (JP18)
Classification of Japanese OTC drugs [BR:br08313]
 Nourishing tonics and health supplements
  34 Vitamin E based drugs
   D01530  Tocopherol nicotinate (JP18)
Drug groups [BR:br08330]
 Hypolipidemic agent
  DG01946  Hypolipidemic agent
   D01530  Tocopherol nicotinate
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01946  Hypolipidemic agent
   D01530  Tocopherol nicotinate
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01530  Tocopherol nicotinate
Other DBs
CAS: 51898-34-1
PubChem: 7848593
ChEBI: 32239
LigandBox: D01530
NIKKAJI: J299.341D
KCF data

ATOM        39
            1   C8y C    17.7100  -30.3800
            2   C8y C    17.7100  -28.9800
            3   C8y C    18.9700  -28.2800
            4   C8y C    18.9700  -31.0800
            5   C8y C    20.1600  -30.3800
            6   C8y C    20.1600  -28.9800
            7   C1x C    21.3500  -28.2800
            8   C1x C    22.6100  -28.9800
            9   C1z C    22.6100  -30.3800
            10  O2x O    21.3500  -31.0800
            11  C1a C    18.9700  -32.4800
            12  C1a C    18.9700  -26.8800
            13  O7a O    16.5200  -28.2800
            14  C7a C    15.3300  -28.9800
            15  C8y C    14.0000  -28.2800
            16  C1b C    23.8000  -31.0800
            17  C1b C    24.9900  -30.3800
            18  C1b C    26.1800  -31.0800
            19  C1c C    27.4400  -30.3800
            20  C1b C    28.6300  -31.0800
            21  C1b C    29.8200  -30.3800
            22  C1b C    31.0800  -31.0800
            23  C1c C    32.2700  -30.3800
            24  C1b C    33.4600  -31.0800
            25  C1b C    34.7200  -30.3800
            26  C1b C    35.9100  -31.0800
            27  C1c C    37.1000  -30.3800
            28  C1a C    38.2900  -31.0800
            29  C1a C    27.4400  -28.9800
            30  C1a C    32.2700  -28.9800
            31  C1a C    37.1000  -28.9800
            32  C8x C    12.8100  -28.9800
            33  C8x C    11.6200  -28.2800
            34  C8x C    11.6200  -26.8800
            35  N5x N    12.8100  -26.1800
            36  C8x C    14.0000  -26.8800
            37  C1a C    16.5200  -31.0800
            38  O6a O    15.3300  -30.3800
            39  C1a C    22.6100  -31.7800
BOND        41
            1     7   8 1
            2    18  19 1
            3     8   9 1
            4    19  20 1
            5     9  10 1
            6    20  21 1
            7    10   5 1
            8    21  22 1
            9    22  23 1
            10    4  11 1
            11   23  24 1
            12    1  37 1
            13   24  25 1
            14    1   2 2
            15   25  26 1
            16    3  12 1
            17   26  27 1
            18    2   3 1
            19   27  28 1
            20    2  13 1
            21   19  29 1 #Down
            22    3   6 2
            23   23  30 1 #Down
            24   13  14 1
            25   27  31 1
            26    5   4 2
            27   14  15 1
            28    4   1 1
            29    9  16 1 #Up
            30    5   6 1
            31   16  17 1
            32   15  32 2
            33   32  33 1
            34   33  34 2
            35   34  35 1
            36   35  36 2
            37   36  15 1
            38    6   7 1
            39   17  18 1
            40   14  38 2
            41    9  39 1