Sulthiame


Entry
D01787                      Drug                                   
Name
Sulthiame (USAN);
Sultiame (JP18);
Ospolot (TN)
Formula
C10H14N2O4S2
Exact mass
290.0395
Mol weight
290.3592
Structure
Class
Neuropsychiatric agent
 DG03199  Antiepileptic agent
Remark
Therapeutic category: 1137
ATC code: N03AX03
Product: D01787<JP>
Efficacy
Antiepileptic, Carbonic anhydrase inhibitor
Comment
Sulfonamide derivative
Interaction
Structure map
map07033  Anticonvulsants
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AX Other antiepileptics
     N03AX03 Sultiame
      D01787  Sulthiame (USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1137  Sulfonamides
     D01787  Sulthiame (USAN); Sultiame (JP18)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03199  Antiepileptic agent
   D01787  Sulthiame
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01787  Sultiame
Other DBs
CAS: 61-56-3
PubChem: 7848849
ChEBI: 32171
PDB-CCD: OSP[PDBj]
LigandBox: D01787
NIKKAJI: J4.400H
KCF data

ATOM        18
            1   C1x C    14.4200  -17.1500
            2   C1x C    14.4200  -18.5500
            3   C1x C    15.6800  -19.2500
            4   C1x C    16.8700  -18.5500
            5   N1y N    16.8700  -17.1500
            6   S2x S    15.6800  -16.4500
            7   O3c O    16.8700  -15.7500
            8   O3c O    14.4200  -15.7500
            9   C8y C    20.3700  -15.1200
            10  C8x C    19.1800  -14.4200
            11  C8x C    20.3700  -16.4500
            12  S4a S    21.5600  -14.4200
            13  C8x C    18.0600  -15.1200
            14  C8x C    19.1800  -17.1500
            15  O3c O    20.7900  -13.1600
            16  N1a N    22.8200  -13.7200
            17  O3c O    22.4000  -15.8900
            18  C8y C    18.0600  -16.4500
BOND        19
            1     3   4 1
            2     4   5 1
            3     5   6 1
            4     6   1 1
            5     6   7 2
            6     1   2 1
            7     6   8 2
            8     2   3 1
            9     9  12 1
            10   10  13 1
            11   11  14 2
            12   12  15 2
            13   12  16 1
            14   12  17 2
            15   13  18 2
            16   18   5 1
            17   14  18 1
            18    9  10 2
            19    9  11 1