| Entry |
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| Name | Clindamycin palmitate hydrochloride (JAN/USP); Cleocin pediatric (TN) | ||||||||||
| Product | |||||||||||
| Generic | CLINDAMYCIN PALMITATE HYDROCHLORIDE (Amneal Pharmaceuticals LLC), CLINDAMYCIN PALMITATE HYDROCHLORIDE (Bryant Ranch Prepack), CLINDAMYCIN PALMITATE HYDROCHLORIDE (Bryant Ranch Prepack), CLINDAMYCIN PALMITATE HYDROCHLORIDE (Greenstone LLC), CLINDAMYCIN PALMITATE HYDROCHLORIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), CLINDAMYCIN PALMITATE HYDROCHLORIDE (InvaGen Pharmaceuticals), CLINDAMYCIN PALMITATE HYDROCHLORIDE (Padagis US LLC), CLEOCIN PEDIATRIC (Pharmacia and Upjohn Company LLC), CLINDAMYCIN PALMITATE HYDROCHLORIDE (Rising Pharmaceuticals), CLINDAMYCIN PALMITATE HYDROCHLORIDE (PEDIATRIC) (Aurobindo Pharma Limited), CLINDAMYCIN PALMITATE HYDROCHLORIDE (PEDIATRIC) (NorthStar Rx LLC) | ||||||||||
| Formula | C34H63ClN2O6S. HCl | ||||||||||
| Exact mass | 698.3862 | ||||||||||
| Mol weight | 699.8528 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Antibacterial DG01578 Lincosamide antibiotic | ||||||||||
| Remark |
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| Efficacy | Antibacterial, Protein biosynthesis inhibitor | ||||||||||
| Disease | Infections due to susceptible strains of streptococci [DS:H00333] Infections due to susceptible strains of staphylococci [DS:H01175] | ||||||||||
| Comment | Semisynthetic lincosamide Active form of prodrug: Clindamycin [DR:D00277] | ||||||||||
| Target | 50S ribosomal subunit | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] D DERMATOLOGICALS D10 ANTI-ACNE PREPARATIONS D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE D10AF Antiinfectives for treatment of acne D10AF01 Clindamycin D01990 Clindamycin palmitate hydrochloride (JAN/USP) <US> G GENITO URINARY SYSTEM AND SEX HORMONES G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS G01AA Antibiotics G01AA10 Clindamycin D01990 Clindamycin palmitate hydrochloride (JAN/USP) <US> J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS J01FF Lincosamides J01FF01 Clindamycin D01990 Clindamycin palmitate hydrochloride (JAN/USP) <US> USP drug classification [BR:br08302] Antibacterials Antibacterials, Other Clindamycin D01990 Clindamycin palmitate hydrochloride (JAN/USP) Dermatological Agents Topical Anti-infectives Antibacterials, dermatological Clindamycin D01990 Clindamycin palmitate hydrochloride (JAN/USP) Drug groups [BR:br08330] Antibacterial DG01578 Lincosamide antibiotic DG00435 Clindamycin D01990 Clindamycin palmitate hydrochloride Drug classes [BR:br08332] Antibacterial DG01578 Lincosamide antibiotic D01990 Clindamycin palmitate hydrochloride Antimicrobials [BR:br08307] Antibacterials Protein biosynthesis inhibitor Lincosamide D01990 Clindamycin palmitate hydrochloride (JAN/USP) <US> Prodrugs [br08324.html] D01990 Drug groups [BR:br08330] Antibacterial DG01578 Lincosamide antibiotic DG00435 Clindamycin Antimicrobials abbreviations [BR:br08327] Antibacterials Protein biosynthesis inhibitor Lincosamide DG00435 Clindamycin Prodrugs [br08324.html] DG00435 | ||||||||||
| Other DBs |
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| KCF data | ATOM 45 1 C1y C 10.6416 -15.4011 2 C1y C 10.6416 -16.8012 3 C1y C 11.8541 -17.5012 4 C1y C 13.0667 -16.8012 5 C1y C 13.0667 -15.4011 6 O2x O 11.8541 -14.7011 7 S2a S 14.2805 -14.7003 8 C1a C 14.2805 -13.3009 9 O7a O 14.2825 -17.5023 10 C7a C 15.4952 -16.8023 11 C1b C 16.7079 -17.5023 12 C1b C 17.9205 -16.8023 13 C1b C 19.1331 -17.5023 14 C1b C 20.3458 -16.8023 15 C1b C 21.5584 -17.5023 16 C1b C 22.7710 -16.8023 17 C1b C 23.9836 -17.5023 18 C1b C 25.1962 -16.8023 19 C1b C 26.4088 -17.5023 20 C1b C 27.6214 -16.8023 21 C1b C 28.8340 -17.5023 22 C1b C 30.0466 -16.8023 23 C1b C 31.2593 -17.5023 24 C1b C 32.4718 -16.8023 25 C1a C 33.6846 -17.5023 26 O1a O 11.8541 -18.9026 27 O1a O 9.4295 -17.5009 28 C1c C 9.4304 -14.7018 29 N1b N 8.2170 -15.4023 30 C1c C 9.4304 -13.3017 31 X Cl 8.2171 -12.6012 32 C1a C 10.6423 -12.6020 33 C5a C 7.0033 -14.7020 34 C1y C 5.7906 -15.4020 35 O5a O 7.0031 -13.3017 36 N1y N 4.5099 -14.8319 37 C1x C 3.5720 -15.8736 38 C1y C 4.2728 -17.0877 39 C1x C 5.6441 -16.7962 40 C1a C 4.2218 -13.4758 41 C1b C 3.7093 -18.3540 42 C1b C 2.2975 -18.5028 43 C1a C 1.7342 -19.7685 44 O6a O 15.4952 -15.3995 45 X Cl 36.7255 -16.3329 BOND 45 1 1 2 1 2 2 3 1 3 3 4 1 4 4 5 1 5 5 6 1 6 1 6 1 7 5 7 1 #Down 8 7 8 1 9 4 9 1 #Down 10 9 10 1 11 10 11 1 12 11 12 1 13 12 13 1 14 13 14 1 15 14 15 1 16 15 16 1 17 16 17 1 18 17 18 1 19 18 19 1 20 19 20 1 21 20 21 1 22 21 22 1 23 22 23 1 24 23 24 1 25 24 25 1 26 3 26 1 #Up 27 2 27 1 #Up 28 1 28 1 29 28 29 1 30 28 30 1 31 30 31 1 #Up 32 30 32 1 33 29 33 1 34 34 33 1 #Down 35 33 35 2 36 34 36 1 37 36 37 1 38 37 38 1 39 38 39 1 40 34 39 1 41 36 40 1 42 38 41 1 #Up 43 41 42 1 44 42 43 1 45 10 44 2 |