| Entry |
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| Name | Betamethasone butyrate propionate (JAN); Antebate (TN) | ||||||||||
| Formula | C29H39FO7 | ||||||||||
| Exact mass | 518.268 | ||||||||||
| Mol weight | 518.6142 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Anti-inflammatory DG01955 Corticosteroid DG02068 Glucocorticoid | ||||||||||
| Remark |
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| Efficacy | Anti-inflammatory, Glucocorticoid receptor agonist | ||||||||||
| Target | NR3C1 (GR) [HSA:2908] [KO:K05771] | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] A ALIMENTARY TRACT AND METABOLISM A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS A07E INTESTINAL ANTIINFLAMMATORY AGENTS A07EA Corticosteroids acting locally A07EA04 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> C CARDIOVASCULAR SYSTEM C05 VASOPROTECTIVES C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE C05AA Corticosteroids C05AA05 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> D DERMATOLOGICALS D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS D07A CORTICOSTEROIDS, PLAIN D07AC Corticosteroids, potent (group III) D07AC01 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> D07X CORTICOSTEROIDS, OTHER COMBINATIONS D07XC Corticosteroids, potent, other combinations D07XC01 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS H02 CORTICOSTEROIDS FOR SYSTEMIC USE H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN H02AB Glucocorticoids H02AB01 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> R RESPIRATORY SYSTEM R01 NASAL PREPARATIONS R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE R01AD Corticosteroids R01AD06 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS R03BA Glucocorticoids R03BA04 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01B ANTIINFLAMMATORY AGENTS S01BA Corticosteroids, plain S01BA06 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION S01CB Corticosteroids/antiinfectives/mydriatics in combination S01CB04 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> S02 OTOLOGICALS S02B CORTICOSTEROIDS S02BA Corticosteroids S02BA07 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS S03B CORTICOSTEROIDS S03BA Corticosteroids S03BA03 Betamethasone D02032 Betamethasone butyrate propionate (JAN) <JP> USP drug classification [BR:br08302] Dermatological Agents Dermatitis and Pruitus Agents Glucocorticoids, Medium Potency Betamethasone D02032 Betamethasone butyrate propionate (JAN) Glucocorticoids, High Potency Betamethasone D02032 Betamethasone butyrate propionate (JAN) Glucocorticoids, Very High Potency Betamethasone D02032 Betamethasone butyrate propionate (JAN) Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 26 Epidermides 264 Analgesics, anti-itchings, astringents, anti-inflammatory agents 2646 Adrenocorticotropic hormones D02032 Betamethasone butyrate propionate (JAN) Drug groups [BR:br08330] Anti-inflammatory DG01955 Corticosteroid DG02068 Glucocorticoid DG00095 Betamethasone D02032 Betamethasone butyrate propionate Drug classes [BR:br08332] Anti-inflammatory DG01955 Corticosteroid D02032 Betamethasone butyrate propionate Target-based classification of drugs [BR:br08310] Nuclear receptors Estrogen like receptors 3-Ketosteroid receptor NR3C1 (GR) D02032 Betamethasone butyrate propionate (JAN) <JP> Topical steroids potency [br08317.html] Classification in Japan D02032 Drug groups [BR:br08330] Anti-inflammatory DG01955 Corticosteroid DG02068 Glucocorticoid DG00095 Betamethasone | ||||||||||
| Other DBs |
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| KCF data | ATOM 37 1 C2x C 15.6561 -19.4690 2 C5x C 15.6561 -20.8194 3 C2x C 16.8256 -21.4948 4 C2y C 17.9952 -20.8194 5 C1z C 17.9952 -19.4690 6 C2x C 16.8256 -18.7937 7 C1x C 19.1647 -21.4948 8 C1x C 20.3344 -20.8194 9 C1y C 20.3344 -19.4690 10 C1z C 19.1647 -18.7937 11 C1y C 21.5039 -18.7937 12 C1z C 21.5039 -17.4432 13 C1x C 20.3344 -16.7679 14 C1y C 19.1647 -17.4432 15 C1x C 23.8430 -18.7937 16 C1y C 23.8430 -17.4432 17 C1z C 22.6735 -16.7679 18 C1a C 25.2197 -17.4517 19 C5a C 22.6737 -15.0019 20 C1a C 21.4866 -16.0984 21 O1a O 17.9476 -16.7404 22 C1a C 17.9831 -18.0546 23 O5x O 14.4453 -21.5185 24 X F 19.1493 -20.2006 25 O7a O 23.9078 -16.0487 26 O5a O 23.9029 -14.2923 27 C1b C 21.4828 -14.2991 28 O7a O 20.2708 -14.9989 29 C7a C 19.0588 -14.2991 30 C1b C 17.8467 -14.9989 31 O6a O 19.0588 -12.8996 32 C1a C 16.6320 -14.2975 33 C7a C 26.0073 -16.0487 34 O6a O 26.7103 -17.2661 35 C1b C 26.6970 -14.8538 36 C1b C 28.0922 -14.8536 37 C1a C 28.7947 -13.6363 BOND 40 1 1 2 1 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 1 6 1 6 2 7 4 7 1 8 7 8 1 9 8 9 1 10 9 10 1 11 5 10 1 12 9 11 1 13 11 12 1 14 12 13 1 15 13 14 1 16 10 14 1 17 11 15 1 18 15 16 1 19 16 17 1 20 12 17 1 21 16 18 1 #Up 22 17 19 1 #Up 23 12 20 1 #Up 24 14 21 1 #Up 25 5 22 1 #Up 26 2 23 2 27 10 24 1 #Down 28 17 25 1 #Down 29 19 26 2 30 19 27 1 31 27 28 1 32 28 29 1 33 29 30 1 34 29 31 2 35 30 32 1 36 25 33 1 37 33 34 2 38 33 35 1 39 35 36 1 40 36 37 1 |