Entry

D02119                      Drug

Name

Ampicillin sodium (JP18/USP);
Omnipen-N (TN);
Viccillin (TN)

Product

Generic

AMPICILLIN (Civica), AMPICILLIN (General Injectables and Vaccines), AMPICILLIN (HF Acquisition Co LLC), AMPICILLIN (HF Acquisition Co LLC), AMPICILLIN (Henry Schein), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Mylan Institutional LLC), AMPICILLIN (Piramal Critical Care), AMPICILLIN (Piramal Critical Care), AMPICILLIN (Sagent Pharmaceuticals), AMPICILLIN (WG Critical Care), AMPICILLIN (WG Critical Care), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Methapharm), AMPICILLIN (A-S Medication Solutions), AMPICILLIN (Athenex Pharmaceutical Division), AMPICILLIN (Athenex Pharmaceutical Division), AMPICILLIN (AuroMedics Pharma LLC), AMPICILLIN (AuroMedics Pharma LLC), AMPICILLIN (Fresenius Kabi USA), AMPICILLIN (General Injectables and Vaccines), AMPICILLIN (General Injectables and Vaccines), AMPICILLIN (Henry Schein), AMPICILLIN (Henry Schein), AMPICILLIN (Hospira), AMPICILLIN (Hospira), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN (Medical Purchasing Solutions), AMPICILLIN SODIUM (Mylan Institutional LLC), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Sandoz), AMPICILLIN (Xellia Pharmaceuticals USA LLC), AMPICILLIN (Xellia Pharmaceuticals USA LLC)

Formula

C16H18N3O4S. Na

Exact mass

371.0916

Mol weight

371.3866

Structure

Simcomp

Class

Antibacterial
DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penicillin
DG01780  Extended spectrum penicillin

Remark

Same as:

C13652

Therapeutic category:

6131

ATC code:

J01CA01 S01AA19

Chemical structure group:

DG00517

Product (DG00517):

D01251<JP/US> D02119<JP/US>

Product (mixture):

D02065<JP/US> D02502<JP>

Efficacy

Antibacterial, Cell wall biosynthesis inhibitor

Disease

Bacterial endocarditis [DS:H00334]

Target

penicillin binding protein

Pathway

ko00550

Peptidoglycan biosynthesis

Interaction

Structure map

map07011

Penicillins

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA01 Ampicillin
      D02119  Ampicillin sodium (JP18/USP) <JP/US>
S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA19 Ampicillin
      D02119  Ampicillin sodium (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
  Beta-lactam, Penicillins
   Ampicillin
    D02119  Ampicillin sodium (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6131  Penicillins
     D02119  Ampicillin sodium (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00517  Ampicillin
      D02119  Ampicillin sodium
  DG01780  Extended spectrum penicillin
   DG00517  Ampicillin
    D02119  Ampicillin sodium
Drug classes [BR:br08332]
Antibacterial
  DG01480  Penicillin
   D02119  Ampicillin sodium
Antimicrobials [BR:br08307]
Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D02119  Ampicillin sodium (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D02119  Ampicillin sodium
  D02119  Ampicillin sodium for injection
Drug groups [BR:br08330]
Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00517  Ampicillin
  DG01780  Extended spectrum penicillin
   DG00517  Ampicillin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00517  Ampicillin

Other DBs

CAS:

69-52-3

PubChem:

7849180

ChEBI:

34535

LigandBox:

D02119

NIKKAJI:

J4.868B

KCF data

ATOM        25
            1   C1y C    28.4025  -14.8702
            2   C5x C    28.4025  -16.2751
            3   N1y N    29.8073  -16.2751
            4   C1y C    29.8073  -14.8702
            5   C1y C    31.1418  -16.6964
            6   C1z C    31.9845  -15.5725
            7   S2x S    31.1418  -14.4487
            8   C1a C    32.9680  -16.5559
            9   C1a C    32.9680  -14.5892
            10  C6a C    31.6334  -18.0309
            11  O6a O    33.0381  -18.0309 #-
            12  O6a O    30.7905  -19.1546
            13  N1b N    27.2084  -14.1678
            14  C5a C    26.0144  -14.8702
            15  O5x O    27.2084  -16.9774
            16  O5a O    26.0144  -16.2751
            17  C1c C    24.7949  -14.1727
            18  C8y C    23.6026  -14.8679
            19  N1a N    24.7949  -12.7715
            20  C8x C    22.3890  -14.1673
            21  C8x C    21.1757  -14.8679
            22  C8x C    21.1757  -16.2692
            23  C8x C    22.3890  -16.9698
            24  C8x C    23.6026  -16.2692
            25  Z   Na   34.5800  -18.0600 #+
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1