Cefaclor

Entry

D02352                      Drug

Name

Cefaclor (USP);
Cefaclor monohydrate;
Ceclor (TN)

Product

Generic

CEFACLOR (A-S Medication Solutions), CEFACLOR (Aytu Therapeutics), CEFACLOR (Carlsbad Technology), CEFACLOR (Hikma Pharmaceuticals USA), CEFACLOR (Teva Pharmaceuticals USA)

Formula

C15H14ClN3O4S. H2O

Exact mass

385.0499

Mol weight

385.8226

Structure

Simcomp

Class

Antibacterial
DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
DG01775  Second-generation cephalosporin

Remark

ATC code:

J01DC04

Chemical structure group:

DG00560

Product (DG00560):

D00256<JP> D02352<US>

Efficacy

Antibacterial, Cell wall biosynthesis inhibitor

Target

penicillin binding protein

Pathway

ko00550

Peptidoglycan biosynthesis

Interaction

Structure map

map07013

Cephalosporins - oral agents

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DC Second-generation cephalosporins
     J01DC04 Cefaclor
      D02352  Cefaclor (USP) <US>
USP drug classification [BR:br08302]
Antibacterials
  Beta-lactam, Cephalosporins
   Cefaclor
    D02352  Cefaclor (USP)
Drug groups [BR:br08330]
Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00560  Cefaclor
      D02352  Cefaclor
  DG01775  Second-generation cephalosporin
   DG00560  Cefaclor
    D02352  Cefaclor
Drug classes [BR:br08332]
Antibacterial
  DG01488  Cephem
   D02352  Cefaclor
Antimicrobials [BR:br08307]
Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Second-generation cephalosporin
    D02352  Cefaclor (USP) <US>
Drug groups [BR:br08330]
Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00560  Cefaclor
  DG01775  Second-generation cephalosporin
   DG00560  Cefaclor
Antimicrobials abbreviations [BR:br08327]
Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Second-generation cephalosporin
    DG00560  Cefaclor

Other DBs

CAS:	70356-03-5

PubChem:

7849411

LigandBox:

D02352

KCF data

ATOM        25
            1   C1y C    29.3164  -14.8915
            2   N1y N    29.3164  -16.2906
            3   C2y C    30.5281  -16.9900
            4   C2y C    31.7398  -16.2906
            5   C1x C    31.7398  -14.8915
            6   S2x S    30.5281  -14.1919
            7   C1y C    27.9173  -14.8915
            8   C5x C    27.9173  -16.2906
            9   N1b N    26.7057  -14.1919
            10  C5a C    25.4938  -14.8915
            11  O5a O    25.4938  -16.2906
            12  O5x O    26.7057  -16.9900
            13  C1c C    24.2822  -14.1919
            14  X   Cl   32.9701  -17.0012
            15  C6a C    30.5281  -18.3890
            16  O6a O    29.2996  -19.0984
            17  O6a O    31.7228  -19.0789
            18  C8y C    23.0510  -14.9031
            19  C8x C    21.8409  -14.2044
            20  C8x C    20.6307  -14.9031
            21  C8x C    20.6307  -16.3005
            22  C8x C    21.8409  -16.9992
            23  C8x C    23.0510  -16.3005
            24  N1a N    24.2822  -12.7883
            25  O0  O    34.7200  -15.0500
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up