Cefadroxil

Entry

D02353                      Drug

Name

Cefadroxil (USP);
Cefadroxil monohydrate;
Duricef (TN)

Product

Generic

CEFADROXIL (A-S Medication Solutions), CEFADROXIL (A-S Medication Solutions), CEFADROXIL (A-S Medication Solutions), CEFADROXIL (Aurobindo Pharma Limited), CEFADROXIL (Aurobindo Pharma Limited), CEFADROXIL (Bryant Ranch Prepack), CEFADROXIL (Bryant Ranch Prepack), CEFADROXIL (Bryant Ranch Prepack), CEFADROXIL (Bryant Ranch Prepack), CEFADROXIL (DIRECT RX), CEFADROXIL (Denton Pharma), CEFADROXIL (Denton Pharma), CEFADROXIL (Hikma Pharmaceuticals USA), CEFADROXIL (Hikma Pharmaceuticals USA), CEFADROXIL (Hikma Pharmaceuticals USA), CEFADROXIL (Lupin Pharmaceuticals), CEFADROXIL (Lupin Pharmaceuticals), CEFADROXIL (NorthStar Rx LLC), CEFADROXIL (NorthStar Rx LLC), CEFADROXIL (NuCare Pharmaceuticals), CEFADROXIL (NuCare Pharmaceuticals), CEFADROXIL (NuCare Pharmaceuticals), CEFADROXIL (NuCare Pharmaceuticals), CEFADROXIL (NuCare Pharmaceuticals), CEFADROXIL (NuCare Pharmaceuticals), CEFADROXIL (PD-Rx Pharmaceuticals), CEFADROXIL (PD-Rx Pharmaceuticals), CEFADROXIL (PD-Rx Pharmaceuticals), CEFADROXIL (Preferred Pharmaceuticals), CEFADROXIL (Proficient Rx LP), CEFADROXIL (REMEDYREPACK), CEFADROXIL (RPK Pharmaceuticals), CEFADROXIL (RedPharm Drug), CEFADROXIL (RedPharm Drug), CEFADROXIL (Rising Health), CEFADROXIL (Rising Health), CEFADROXIL (Teva Pharmaceuticals USA), CEFADROXIL (Teva Pharmaceuticals USA), CEFADROXIL (medsource pharmaceutocals)

Formula

C16H17N3O5S. H2O

Exact mass

381.0995

Mol weight

381.4036

Structure

Simcomp

Class

Antibacterial
DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01488  Cephem
DG01774  First-generation cephalosporin

Remark

ATC code:

J01DB05

Chemical structure group:

DG00551

Product (DG00551):

D02353<US>

Efficacy

Antibacterial, Cell wall biosynthesis inhibitor

Target

penicillin binding protein

Pathway

ko00550

Peptidoglycan biosynthesis

Interaction

Structure map

map07013

Cephalosporins - oral agents

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB05 Cefadroxil
      D02353  Cefadroxil (USP) <US>
USP drug classification [BR:br08302]
Antibacterials
  Beta-lactam, Cephalosporins
   Cefadroxil
    D02353  Cefadroxil (USP)
Drug groups [BR:br08330]
Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00551  Cefadroxil
      D02353  Cefadroxil
  DG01774  First-generation cephalosporin
   DG00551  Cefadroxil
    D02353  Cefadroxil
Drug classes [BR:br08332]
Antibacterial
  DG01488  Cephem
   D02353  Cefadroxil
Antimicrobials [BR:br08307]
Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   First-generation cephalosporin
    D02353  Cefadroxil (USP) <US>
Drug groups [BR:br08330]
Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01488  Cephem
     DG00551  Cefadroxil
  DG01774  First-generation cephalosporin
   DG00551  Cefadroxil
Antimicrobials abbreviations [BR:br08327]
Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   First-generation cephalosporin
    DG00551  Cefadroxil

Other DBs

CAS:	66592-87-8

PubChem:

7849412

ChEBI:

53667

LigandBox:

D02353

NIKKAJI:

J252.792H

KCF data

ATOM        26
            1   C1y C    30.2264  -14.8915
            2   N1y N    30.2264  -16.2906
            3   C2y C    31.4381  -16.9900
            4   C2y C    32.6498  -16.2906
            5   C1x C    32.6498  -14.8915
            6   S2x S    31.4381  -14.1919
            7   C1y C    28.8273  -14.8915
            8   C5x C    28.8273  -16.2906
            9   N1b N    27.6157  -14.1919
            10  C5a C    26.4038  -14.8915
            11  O5a O    26.4038  -16.2906
            12  O5x O    27.6157  -16.9900
            13  C1c C    25.1922  -14.1919
            14  C1a C    33.8801  -17.0012
            15  C6a C    31.4381  -18.3890
            16  O6a O    30.2096  -19.0984
            17  O6a O    32.6328  -19.0789
            18  C8y C    23.9610  -14.9031
            19  C8x C    22.7509  -14.2044
            20  C8x C    21.5407  -14.9031
            21  C8y C    21.5407  -16.3005
            22  C8x C    22.7509  -16.9992
            23  C8x C    23.9610  -16.3005
            24  N1a N    25.1922  -12.7883
            25  O1a O    20.3421  -16.9928
            26  O0  O    35.6300  -15.0500
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up
            27   21  25 1