| Entry |
|
|---|
| Name |
Interferon alfa-2b (USAN);
Interferon alfa-2b (genetical recombination) (JAN);
Intron A (TN) |
|---|
| Product |
INTRON A (Merck Sharp & Dohme LLC) |
|---|
| Formula |
C860H1353N229O255S9
|
|---|
| Exact mass |
19256.7431
|
|---|
| Mol weight |
19268.9111
|
|---|
| Sequence |
CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI
QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR
KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE |
|---|
| Type |
Peptide |
|---|
| Class |
Immunological agent
DG01752 Interferone
|
|---|
| Remark |
| Chemical structure group: | DG01750 |
| Product (DG01750): | D02745<US> D03305<JP> D04553<US> |
|
|---|
| Efficacy |
Antineoplastic, Antiviral, Biological response modifier |
|---|
| Disease |
Hairy cell leukemia [DS:H00006]
Malignant melanoma [DS:H00038]
Follicular lymphoma [DS:H01613]
Condylomata acuminata [DS:H01418]
AIDS-related Kaposi's sarcoma [DS:H00041]
Chronic hepatitis C [DS:H00413]
Chronic hepatitis B [DS:H00412] |
|---|
| Target |
IFNAR1 [HSA:3454] [KO:K05130]
IFNAR2 [HSA:3455] [KO:K05131] |
|---|
| Pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
| hsa04620 | Toll-like receptor signaling pathway |
| hsa04630 | JAK-STAT signaling pathway |
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
| hsa05200 | Pathways in cancer |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07044 | Antiviral agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L03 IMMUNOSTIMULANTS
L03A IMMUNOSTIMULANTS
L03AB Interferons
L03AB05 Interferon alfa-2b
D02745 Interferon alfa-2b (USAN) <US>
USP drug classification [BR:br08302]
Immunological Agents
Immunostimulants
Interferons
Interferon Alfa 2B
D02745 Interferon alfa-2b (USAN)
Drug groups [BR:br08330]
Immunological agent
DG01752 Interferone
DG01750 Interferon alpha
D02745 Interferon alfa-2b
Drug classes [BR:br08332]
Immunological agent
DG01752 Interferone
D02745 Interferon alfa-2b
Target-based classification of drugs [BR:br08310]
Cytokines and receptors
Cytokine receptors
Interferon receptors
IFNAR1
D02745 Interferon alfa-2b (USAN) <US>
IFNAR2
D02745 Interferon alfa-2b (USAN) <US>
Antimicrobials [BR:br08307]
Antivirals
Entry, fusion or uncoating inhibitor
Interferon
D02745 Interferon alfa-2b (USAN) <US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D02745
Drug groups [BR:br08330]
Immunological agent
DG01752 Interferone
DG01750 Interferon alpha
Antimicrobials abbreviations [BR:br08327]
Antivirals
Entry, fusion or uncoating inhibitor
Interferon
DG01750 Interferon alpha
|
|---|
| Other DBs |
|
|---|