| Entry |
| ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Name | Adefovir (USAN/INN) | ||||||||||||
| Formula | C8H12N5O4P | ||||||||||||
| Exact mass | 273.0627 | ||||||||||||
| Mol weight | 273.1857 | ||||||||||||
| Structure |  | ||||||||||||
| Simcomp | |||||||||||||
| Class | Antiviral DG01890 Nucleoside reverse transcriptase inhibitor (NRTI) | ||||||||||||
| Remark |
| ||||||||||||
| Efficacy | Antiviral, Reverse transcriptase inhibitor | ||||||||||||
| Target | HBV reverse transcriptase [KO:K21037] | ||||||||||||
| Pathway |
| ||||||||||||
| Brite | Drug groups [BR:br08330] Antiviral DG01890 Nucleoside reverse transcriptase inhibitor (NRTI) DG01224 Adefovir D02768 Adefovir Antimicrobials [BR:br08307] Antivirals Genome replication inhibitor HBV reverse transcriptase inhibitor D02768 Adefovir (USAN/INN) Prodrugs [br08324.html] D02768 Drug groups [BR:br08330] Antiviral DG01890 Nucleoside reverse transcriptase inhibitor (NRTI) DG01224 Adefovir Antimicrobials abbreviations [BR:br08327] Antivirals Genome replication inhibitor HBV reverse transcriptase inhibitor DG01224 Adefovir | ||||||||||||
| Other DBs |
| ||||||||||||
| KCF data | ATOM 18 1 C8y C 30.5268 -18.7216 2 C8y C 30.5268 -17.2550 3 N4y N 29.1998 -19.1407 4 N5x N 31.7839 -19.3502 5 N5x N 29.1998 -16.8359 6 C8y C 31.7839 -16.6263 7 C8x C 28.3617 -18.0232 8 C8x C 32.9713 -18.7216 9 N5x N 32.9713 -17.2550 10 N1a N 31.7839 -15.2295 11 C1b C 29.1998 -20.5407 12 C1b C 27.9935 -21.2370 13 O2a O 26.7745 -20.5331 14 C1b C 25.5469 -21.2424 15 P1b P 24.3227 -20.5365 16 O1c O 23.1102 -19.8365 17 O1c O 23.6264 -21.7427 18 O1c O 25.0255 -19.3188 BOND 19 1 2 5 1 2 2 6 1 3 3 7 1 4 4 8 2 5 6 9 2 6 5 7 2 7 8 9 1 8 1 2 2 9 1 3 1 10 1 4 1 11 6 10 1 12 3 11 1 13 11 12 1 14 12 13 1 15 13 14 1 16 14 15 1 17 15 16 1 18 15 17 1 19 15 18 2 |