| Entry |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Name | Doxycycline calcium (USP) | ||||||||
| Formula | C22H20N2O8. 2Ca | ||||||||
| Exact mass | 520.0471 | ||||||||
| Mol weight | 520.5588 | ||||||||
| Structure |  | ||||||||
| Simcomp | |||||||||
| Class | Antibacterial DG01197 Tetracycline antibiotic | ||||||||
| Remark |
| ||||||||
| Efficacy | Antibacterial, Antiprotozoal, Protein biosynthesis inhibitor | ||||||||
| Disease | Rocky Mountain spotted fever [DS:H00323] Typhus fever [DS:H00322] Q fever [DS:H00310] Lymphogranuloma venereum [DS:H00348] Psittacosis [DS:H00350] Trachoma [DS:H00349] Relapsing fever [DS:H00427] Chancroid [DS:H00305] Plague [DS:H00297] Tularemia [DS:H00312] Cholera [DS:H00110] Campylobacter fetus infection [DS:H00321] Brucellosis [DS:H00325] Bartonellosis [DS:H00326] Granuloma inguinale [DS:H01415] Anthrax [DS:H00328] Gonorrhea [DS:H00315] Syphilis [DS:H00354] Yaws [DS:H01318] Listeriosis [DS:H00332] Vincent's infection [DS:H01440] Actinomycosis [DS:H01325] Amebiasis [DS:H00360] Severe acne [DS:H01445] Malaria [DS:H00361] | ||||||||
| Target | 30S ribosomal subunit | ||||||||
| Pathway |
| ||||||||
| Interaction | |||||||||
| Structure map |
| ||||||||
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] A ALIMENTARY TRACT AND METABOLISM A01 STOMATOLOGICAL PREPARATIONS A01A STOMATOLOGICAL PREPARATIONS A01AB Antiinfectives and antiseptics for local oral treatment A01AB22 Doxycycline D03903 Doxycycline calcium (USP) J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01A TETRACYCLINES J01AA Tetracyclines J01AA02 Doxycycline D03903 Doxycycline calcium (USP) USP drug classification [BR:br08302] Antibacterials Tetracyclines Doxycycline D03903 Doxycycline calcium (USP) Drug groups [BR:br08330] Antibacterial DG01197 Tetracycline antibiotic DG00008 Doxycycline D03903 Doxycycline calcium Antimicrobials [BR:br08307] Antibacterials Protein biosynthesis inhibitor Tetracycline D03903 Doxycycline calcium (USP) Drug groups [BR:br08330] Antibacterial DG01197 Tetracycline antibiotic DG00008 Doxycycline Antimicrobials abbreviations [BR:br08327] Antibacterials Protein biosynthesis inhibitor Tetracycline DG00008 Doxycycline | ||||||||
| Other DBs |
| ||||||||
| KCF data | ATOM 34 1 Z Ca 29.8200 -20.5939 #2+ 2 C8x C 12.1800 -20.0200 3 C8x C 12.1800 -21.4200 4 C8y C 13.3924 -22.1200 5 C8y C 14.6049 -21.4200 6 C8y C 14.6049 -20.0200 7 C8x C 13.3924 -19.3200 8 C5x C 15.8173 -22.1200 9 C2y C 17.0297 -21.4200 10 C1y C 17.0297 -20.0200 11 C1y C 15.8173 -19.3200 12 C2y C 18.2422 -22.1200 13 C1z C 19.4546 -21.4200 14 C1y C 19.4546 -20.0200 15 C1y C 18.2422 -19.3200 16 C5x C 20.6670 -22.1200 17 C2y C 21.8795 -21.4200 18 C2y C 21.8795 -20.0200 19 C1y C 20.6670 -19.3200 20 C5a C 23.1146 -22.1334 21 N1a N 24.3219 -21.4366 22 O5a O 23.1142 -23.5199 23 O1a O 23.1146 -19.3066 24 N1c N 20.6670 -17.9201 25 C1a C 19.4418 -17.2126 26 C1a C 21.8667 -17.2274 27 O1a O 18.2422 -17.9203 #- 28 C1a C 15.8173 -17.9200 29 O1a O 13.3924 -23.5198 #- 30 O5x O 15.8173 -23.5200 31 O1a O 18.2422 -23.5197 #- 32 O1a O 19.4546 -22.8200 #- 33 O5x O 20.6670 -23.5199 34 Z Ca 29.8200 -20.5939 #2+ BOND 35 1 2 3 1 2 3 4 2 3 4 5 1 4 5 6 2 5 6 7 1 6 2 7 2 7 5 8 1 8 8 9 1 9 9 10 1 10 10 11 1 11 6 11 1 12 9 12 2 13 12 13 1 14 13 14 1 15 14 15 1 16 10 15 1 17 13 16 1 18 16 17 1 19 17 18 2 20 18 19 1 21 14 19 1 22 17 20 1 23 20 21 1 24 20 22 2 25 18 23 1 26 19 24 1 #Down 27 24 25 1 28 24 26 1 29 15 27 1 #Down 30 11 28 1 #Down 31 4 29 1 32 8 30 2 33 12 31 1 34 13 32 1 #Down 35 16 33 2 BRACKET 1 28.4200 -21.9100 28.4200 -18.9700 1 32.2000 -18.9700 32.2000 -21.9100 1 2 ORIGINAL 1 1 REPEAT 1 36 |