Entry

D04052            Mixture   Drug

Name

Epinephrine and lidocaine hydrochloride;
Adrenaline and lidocaine hydrochloride;
Xylocaine (TN)

Product

XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein), XYLOCAINE (Henry Schein)

Generic

LIDOCAINE HCI (HF Acquisition Co LLC), LIDOCAINE HCI (HF Acquisition Co LLC), LIDOCAINE HCI AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCL AND EPINEPHRINE (B. Braun Medical), LIDOCAINE HCL AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCL AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (General Injectables & Vaccines), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (General Injectables & Vaccines), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (General Injectables & Vaccines), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Hospira), LIXTRAXEN 1% (IT3 Medical LLC), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE (Cardinal Health)

Component

Adrenaline [DR:D00095], Lidcaine hydrochloride [DR:D02086]

Class

Metabolizing enzyme substrate
DG01892  CYP1A2 substrate
DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate

Remark

Therapeutic category:

1214 2710

Product:

D04052<JP/US>

Efficacy

Anesthetic (local)

Metabolism

Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576]

Interaction

Brite

USP drug classification [BR:br08302]
Anesthetics
  Local Anesthetics
   Lidocaine/ Epinephrine
    D04052  Epinephrine and lidocaine hydrochloride
Therapeutic category of drugs in Japan [BR:br08301]
1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   121  Local anesthetics
    1214  Xylidines
     D04052  Epinephrine and lidocaine hydrochloride
2  Agents affecting individual organs
  27  Dental preparations
   271  Local anesthetics
    2710  Local anesthetics
     D04052  Epinephrine and lidocaine hydrochloride
Drug groups [BR:br08330]
Metabolizing enzyme substrate
  DG01892  CYP1A2 substrate
   D04052  Epinephrine and lidocaine hydrochloride
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D04052  Epinephrine and lidocaine hydrochloride
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
  D04052

Other DBs

PubChem:

17398016