Entry

D04813            Mixture   Drug

Name

Lidocaine hydrochloride and epinephrine bitartrate;
Lidocaine hydrochloride and adrenaline bitartrate;
Ora (TN);
Lidosite (TN)

Product

LIDOCAINE HCI AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCI AND EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCI AND EPINEPHRINE WITH EPINEPHRINE (HF Acquisition Co LLC), LIDOCAINE HCL AND EPI (HF Acquisition Co LLC), XYLOCAINE (General Injectables & Vaccines), XYLOCAINE (General Injectables & Vaccines), XYLOCAINE (General Injectables & Vaccines), XYLOCAINE (General Injectables & Vaccines), XYLOCAINE (A-S Medication Solutions), XYLOCAINE (Fresenius Kabi USA), XYLOCAINE (Fresenius Kabi USA), XYLOCAINE(R) -MPF (LIDOCAINE HCI AND EPINEPHRINE) (HF Acquisition Co LLC), XYLOCAINE-MPF WITH EPI (HF Acquisition Co LLC)

Generic

LIDOCAINE (Septodont), LIDOCAINE (Septodont), LIGNOSPAN FORTE (Septodont), LIGNOSPAN STANDARD (Septodont), LIDOCAINE (Benco Dental), LIDOCAINE (Benco Dental), LIDOCAINE (Darby Dental Supply), LIDOCAINE (Darby Dental Supply), XYLOCAINE (Dentsply Pharmaceutical), LIDOCAINE (Henry Schein), LIDOCAINE (Henry Schein), LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE (IQ Dental), LIDOCAINE (NDC), LIDOCAINE (Patterson Dental), LIDOCAINE (Patterson Dental), LIDOCAINE (Safco Dental Supply), LIDOCAINE (The Atlanta Dental Supply Company DBA Advanced Dental Products)

Component

(Lidocaine hydrochloride [DR:D02086] | Lidocaine hydrochloride monohydrate [DR:D08127]), Epinephrine bitartrate [DR:D02149]

Class

Metabolizing enzyme substrate
DG01892  CYP1A2 substrate
DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate

Remark

Therapeutic category:

2710

Product:

D04813<JP/US>

Efficacy

Anesthetic (topical, dental)

Metabolism

Enzyme: CYP1A2 [HSA:1544], CYP3A4 [HSA:1576]

Interaction

Brite

USP drug classification [BR:br08302]
Anesthetics
  Local Anesthetics
   Lidocaine/ Epinephrine
    D04813  Lidocaine hydrochloride and epinephrine bitartrate
Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  27  Dental preparations
   271  Local anesthetics
    2710  Local anesthetics
     D04813  Lidocaine hydrochloride and epinephrine bitartrate
Drug groups [BR:br08330]
Metabolizing enzyme substrate
  DG01892  CYP1A2 substrate
   D04813  Lidocaine hydrochloride and epinephrine bitartrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D04813  Lidocaine hydrochloride and epinephrine bitartrate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
  D04813

Other DBs

PubChem:

17398182