| Entry |
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|---|---|---|---|---|---|---|---|
| Name | Azithromycin (USP); Zmax (TN) | ||||||
| Product | AZASITE (Akorn) | ||||||
| Generic | AZITHROMYCIN (A-S Medication Solutions), AZITHROMYCIN (Aphena Pharma Solutions - Tennessee), AZITHROMYCIN (Asclemed USA), AZITHROMYCIN (AuroMedics Pharma LLC), AZITHROMYCIN (DirectRx), AZITHROMYCIN (Epic Pharma), AZITHROMYCIN (Hospira), AZITHROMYCIN (Hospira), AZITHROMYCIN (Lupin Pharmaceuticals), AZITHROMYCIN (Medsource Pharmaceuticals), AZITHROMYCIN (Mylan Institutional LLC), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (NuCare Pharmaceuticals), AZITHROMYCIN (PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS), AZITHROMYCIN (Preferred Pharmaceuticals), AZITHROMYCIN (Preferred Pharmaceuticals), AZITHROMYCIN (Preferred Pharmaceuticals), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Proficient Rx LP), AZITHROMYCIN (Quality Care Products LLC), AZITHROMYCIN (Quality Care Products), AZITHROMYCIN (REMEDYREPACK), AZITHROMYCIN (REMEDYREPACK), AZITHROMYCIN (REMEDYREPACK), AZITHROMYCIN (REMEDYREPACK), AZITHROMYCIN (RPK Pharmaceuticals), AZITHROMYCIN (RPK Pharmaceuticals), AZITHROMYCIN (RPK Pharmaceuticals), AZITHROMYCIN (RPK Pharmaceuticals), AZITHROMYCIN (RPK Pharmaceuticals), AZITHROMYCIN (STATE HEALTH SERVICES), AZITHROMYCIN (Sandoz), AZITHROMYCIN (Sandoz), AZITHROMYCIN (St. Mary's Medical Park Pharmacy), AZITHROMYCIN (Sun Pharmaceutical Industries), AZITHROMYCIN (Teva Pharmaceuticals USA), AZITHROMYCIN (Teva Pharmaceuticals USA), AZITHROMYCIN (Teva Pharmaceuticals USA), AZITHROMYCIN (PharmPak), AZITHROMYCIN MONOHYDRATE (American Health Packaging), AZITHROMYCIN MONOHYDRATE (American Health Packaging), AZITHROMYCIN MONOHYDRATE (Amneal Pharmaceuticals LLC), AZITHROMYCIN (Athenex Pharmaceutical Division), AZITHROMYCIN (Athenex Pharmaceutical Division), AZITHROMYCIN MONOHYDRATE (Cardinal Health 107), AZITHROMYCIN MONOHYDRATE (DIRECT RX), AZITHROMYCIN MONOHYDRATE (Direct_Rx), AZITHROMYCIN (Fresenius Kabi USA), AZITHROMYCIN (Fresenius Kabi USA), AZITHROMYCIN (Fresenius Kabi USA), AZITHROMYCIN MONOHYDRATE (Gland Pharma Limited), AZITHROMYCIN (Lannett Company), AZITHROMYCIN MONOHYDRATE (Lupin Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (Lupin Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (Major Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (NuCare Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (NuCare Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (PD-Rx Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (PD-Rx Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (PD-Rx Pharmaceuticals), AZITHROMYCIN (PharmPak), AZITHROMYCIN MONOHYDRATE (Preferred Pharmaceuticals), AZITHROMYCIN MONOHYDRATE (Proficient Rx LP), AZITHROMYCIN MONOHYDRATE (Proficient Rx LP), AZITHROMYCIN MONOHYDRATE (REMEDYREPACK), AZITHROMYCIN (REMEDYREPACK), AZITHROMYCIN MONOHYDRATE (REMEDYREPACK), AZITHROMYCIN MONOHYDRATE (RPK Pharmaceuticals), AZITHROMYCIN (Taro Pharmaceuticals U.S.A.) | ||||||
| Formula | C38H72N2O12. xH2O | ||||||
| Structure |  | ||||||
| Simcomp | |||||||
| Class | Antibacterial DG01551 Macrolide antibiotic DG01875 15-Membered ring macrolide antibiotic Transporter substrate DG01665 ABCB1 substrate Transporter inhibitor DG01622 ABCB1 inhibitor | ||||||
| Remark |
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| Efficacy | Antibacterial, Protein biosynthesis inhibitor | ||||||
| Disease | Bacterial conjunctivitis [DS:H01360] | ||||||
| Target | 50S ribosomal subunit | ||||||
| Pathway |
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| Metabolism | Transporter: ABCB1 [HSA:5243] | ||||||
| Interaction | Transporter inhibition: ABCB1 [HSA:5243] | ||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS J01FA Macrolides J01FA10 Azithromycin D06390 Azithromycin (USP) <US> S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01A ANTIINFECTIVES S01AA Antibiotics S01AA26 Azithromycin D06390 Azithromycin (USP) <US> USP drug classification [BR:br08302] Antibacterials Macrolides Azithromycin D06390 Azithromycin (USP) Ophthalmic Agents Ophthalmic Anti-Infectives Antibacterials, Ophthalmic Azithromycin D06390 Azithromycin (USP) Drug groups [BR:br08330] Antibacterial DG01551 Macrolide antibiotic DG01875 15-Membered ring macrolide antibiotic DG00606 Azithromycin D06390 Azithromycin Transporter substrate DG01665 ABCB1 substrate DG00606 Azithromycin D06390 Azithromycin Transporter inhibitor DG01622 ABCB1 inhibitor DG00606 Azithromycin D06390 Azithromycin Drug classes [BR:br08332] Antibacterial DG01551 Macrolide antibiotic D06390 Azithromycin Antimicrobials [BR:br08307] Antibacterials Protein biosynthesis inhibitor Macrolide D06390 Azithromycin (USP) <US> Drug metabolizing enzymes and transporters [br08309.html] Drug transporters D06390 Drug groups [BR:br08330] Antibacterial DG01551 Macrolide antibiotic DG01875 15-Membered ring macrolide antibiotic DG00606 Azithromycin Transporter substrate DG01665 ABCB1 substrate DG00606 Azithromycin Transporter inhibitor DG01622 ABCB1 inhibitor DG00606 Azithromycin Antimicrobials abbreviations [BR:br08327] Antibacterials Protein biosynthesis inhibitor Macrolide DG00606 Azithromycin | ||||||
| Other DBs |
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| KCF data | ATOM 53 1 C1y C 22.6580 -16.6914 2 C1y C 21.4463 -17.3176 3 O2a O 24.2209 -17.6570 4 C1z C 22.7046 -15.3624 5 C1y C 21.4462 -18.6405 6 C1a C 20.6374 -16.2886 7 C1y C 25.5732 -16.8903 8 C1x C 21.9087 -14.7889 9 C1a C 23.8698 -15.9186 10 O1a O 23.8815 -14.6425 11 O2a O 22.1837 -20.5664 12 C1y C 20.2930 -19.2846 13 C1y C 26.2990 -18.1312 14 O2x O 26.2873 -15.6375 15 C1y C 22.3887 -13.5242 16 C1y C 23.7876 -21.2806 17 C7x C 19.1690 -18.5879 18 C1a C 20.2637 -20.6075 19 C1y C 27.7334 -18.1195 20 O1a O 25.5849 -19.3841 21 C1y C 27.7274 -15.6375 22 C1x C 21.5926 -12.7049 23 C1a C 23.4074 -12.9684 24 C1x C 23.7876 -22.7265 25 O2x O 25.0289 -20.5664 26 O7x O 19.1925 -17.2650 27 O6a O 18.2146 -19.5655 28 C1x C 28.4416 -16.8786 29 N1c N 28.4533 -19.3664 30 C1a C 28.4416 -14.3907 31 N1y N 20.3751 -12.6639 32 C1z C 25.0289 -23.4407 33 C1y C 26.2755 -21.2806 34 C1y C 18.0627 -16.5917 35 C1a C 29.8174 -20.2738 36 C1a C 29.7470 -18.6699 37 C1y C 19.2219 -13.2902 38 C1a C 20.4041 -11.2941 39 C1y C 26.2755 -22.7265 40 O2a O 25.0172 -24.7754 41 C1a C 27.5166 -20.5664 42 C1z C 18.0511 -15.2630 43 C1b C 16.9038 -17.2124 44 C1y C 19.2160 -14.6308 45 C1a C 18.0628 -12.6112 46 O1a O 27.5166 -23.4407 47 C1a C 26.1703 -25.4544 48 C1a C 16.7634 -15.7723 49 O1a O 16.9038 -14.1742 50 C1a C 16.8744 -18.5410 51 O1a O 20.3633 -15.3039 52 C1a C 23.8163 -24.1408 53 O0 O 32.1300 -23.5900 BOND 54 1 1 2 1 2 1 3 1 #Down 3 1 4 1 4 2 5 1 5 2 6 1 6 7 3 1 #Down 7 4 8 1 8 4 9 1 #Down 9 4 10 1 #Up 10 5 11 1 #Down 11 5 12 1 12 7 13 1 13 7 14 1 14 8 15 1 15 16 11 1 #Down 16 12 17 1 17 12 18 1 #Up 18 13 19 1 19 13 20 1 #Up 20 14 21 1 21 15 22 1 22 15 23 1 #Down 23 16 24 1 24 16 25 1 25 17 26 1 26 17 27 2 27 19 28 1 28 19 29 1 #Down 29 21 30 1 #Down 30 22 31 1 31 24 32 1 32 25 33 1 33 26 34 1 34 29 35 1 35 29 36 1 36 31 37 1 37 31 38 1 38 32 39 1 39 32 40 1 #Down 40 33 41 1 #Up 41 34 42 1 42 34 43 1 #Down 43 37 44 1 44 37 45 1 #Up 45 39 46 1 #Down 46 40 47 1 47 42 48 1 #Down 48 42 49 1 #Up 49 43 50 1 50 44 51 1 #Up 51 21 28 1 52 33 39 1 53 42 44 1 54 32 52 1 #Up BRACKET 1 30.1000 -24.6400 30.1000 -22.4000 1 32.7600 -22.4000 32.7600 -24.6400 1 x ORIGINAL 1 53 REPEAT 1 |