Entry |
|
Name |
Brivudine (INN); Zostex (TN) |
Abbr |
BVDU |
Formula |
C11H13BrN2O5
|
Exact mass |
332.0008
|
Mol weight |
333.1353
|
Structure |
|
Simcomp |
|
Class |
Antiviral
DG02840 Anti-herpesvirus agent
|
Remark |
|
Efficacy |
Antiviral, DNA polymerase inhibitor |
Target |
HSV1 DNA polymerase [KO:K18964] |
Pathway |
ko03240 | Viral replication |
|
Structure map |
map07044 | Antiviral agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB15 Brivudine
D07249 Brivudine (INN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
D07249 Brivudine
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D07249 Brivudine (INN)
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D07249 Brivudine (INN)
|
Other DBs |
|
KCF data |
ATOM 19
1 C1y C 18.3598 -17.8020
2 N4y N 19.6949 -17.3769
3 O2x O 17.2390 -16.8913
4 C1x C 17.9395 -19.0630
5 C8y C 20.8963 -17.9831
6 C8x C 19.6804 -15.9482
7 C1y C 16.1181 -17.7320
8 C1y C 16.5384 -19.0630
9 N4x N 22.1122 -17.2976
10 O5x O 20.9093 -19.3974
11 C8y C 20.8819 -15.1941
12 C1b C 14.7871 -17.3117
13 C8y C 22.0978 -15.8688
14 C2b C 20.8689 -13.7798
15 O1a O 13.7363 -18.2924
16 O5x O 23.2307 -15.1292
17 C2b C 22.0148 -13.0943
18 X Br 22.0033 -11.6944
19 O1a O 15.6978 -20.1839
BOND 20
1 2 5 1
2 2 6 1
3 3 7 1
4 4 8 1
5 5 9 1
6 5 10 2
7 6 11 2
8 7 12 1 #Up
9 9 13 1
10 11 14 1
11 12 15 1
12 13 16 2
13 7 8 1
14 11 13 1
15 14 17 2
16 1 2 1 #Up
17 17 18 1
18 1 3 1
19 1 4 1
20 8 19 1 #Down
|