Phenglutarimide


Entry
D07301                      Drug                                   
Name
Phenglutarimide (INN)
Formula
C17H24N2O2
Exact mass
288.1838
Mol weight
288.3847
Structure
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: N04AA09
Efficacy
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Target
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA09 Phenglutarimide
      D07301  Phenglutarimide (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    D07301  Phenglutarimide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D07301  Phenglutarimide (INN)
Other DBs
CAS: 1156-05-4
PubChem: 51091638
LigandBox: D07301
NIKKAJI: J7.288E
KCF data

ATOM        21
            1   C5x C    23.4487  -16.0284
            2   C1x C    23.4487  -17.4282
            3   C1x C    24.6610  -18.1282
            4   C1z C    25.8734  -17.4282
            5   C5x C    25.8734  -16.0284
            6   N1x N    24.6610  -15.3284
            7   O5x O    22.2364  -15.3284
            8   O5x O    27.1044  -15.3174
            9   C1b C    27.2733  -17.4282
            10  C8y C    26.2372  -18.7865
            11  C1b C    27.9792  -18.6514
            12  N1c N    29.3978  -18.6520
            13  C1b C    30.1133  -17.4147
            14  C1b C    30.0827  -19.8392
            15  C1a C    31.4979  -17.4158
            16  C1a C    31.4976  -19.8400
            17  C8x C    25.5907  -19.9950
            18  C8x C    26.3223  -21.1886
            19  C8x C    27.7218  -21.2218
            20  C8x C    28.3764  -19.9458
            21  C8x C    27.6448  -18.7522
BOND        22
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 2
            8     5   8 2
            9     4   9 1
            10    4  10 1
            11    9  11 1
            12   11  12 1
            13   12  13 1
            14   12  14 1
            15   13  15 1
            16   14  16 1
            17   10  17 2
            18   17  18 1
            19   18  19 2
            20   19  20 1
            21   20  21 2
            22   10  21 1