Bornaprine


Entry
D07302                      Drug                                   
Name
Bornaprine (INN)
Formula
C21H31NO2
Exact mass
329.2355
Mol weight
329.4763
Structure
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: N04AA11
Efficacy
Antiparkinsonian
Target
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA11 Bornaprine
      D07302  Bornaprine (INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01491  Muscarinic cholinergic receptor antagonist
   DG01745  Anticholinergic antiparkinson agent
    D07302  Bornaprine
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D07302  Bornaprine (INN)
Other DBs
CAS: 20448-86-6
PubChem: 51091639
LigandBox: D07302
NIKKAJI: J10.942H
KCF data

ATOM        24
            1   C1x C    11.5500  -15.8900
            2   C1x C    11.5500  -17.2900
            3   C1y C    12.7624  -17.9900
            4   C1x C    13.9749  -17.2900
            5   C1z C    13.9749  -15.8900
            6   C1y C    12.7624  -15.1900
            7   C8y C    13.9749  -14.4900
            8   C7a C    15.1873  -16.5900
            9   O7a O    16.4024  -15.8900
            10  C1b C    17.6149  -16.5900
            11  C1b C    18.8273  -15.8900
            12  C1b C    20.0397  -16.5900
            13  N1c N    21.2522  -15.8900
            14  C8x C    15.2060  -13.7790
            15  C8x C    15.2058  -12.3790
            16  C8x C    13.9933  -11.6792
            17  C8x C    12.7622  -12.3902
            18  C8x C    12.7624  -13.7902
            19  O6a O    15.1867  -17.9900
            20  C1b C    22.4853  -16.6022
            21  C1b C    21.2523  -14.4903
            22  C1a C    22.4855  -13.7781
            23  C1a C    23.6915  -15.9060
            24  C1x C    12.0624  -16.4024
BOND        26
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     5   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    7  14 2
            15   14  15 1
            16   15  16 2
            17   16  17 1
            18   17  18 2
            19    7  18 1
            20    8  19 2
            21   13  20 1
            22   13  21 1
            23   21  22 1
            24   20  23 1
            25    6  24 1
            26   24   3 1