Triclabendazole

Entry

D07364                      Drug

Name

Triclabendazole (USAN/INN);
Egaten (TN);
Fasinex (TN)

Product

EGATEN (Novartis Pharmaceuticals Corporation)

Formula

C14H9Cl3N2OS

Exact mass

357.9501

Mol weight

359.6581

Structure

Remark

ATC code:

P02BX04

Product:

D07364<US>

Efficacy

Anthelmintic

Disease

Fascioliasis [DS:H01048]

Comment

Benzimidazole derivative
veterinary medicine

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P02 ANTHELMINTICS
   P02B ANTITREMATODALS
    P02BX Other antitrematodal agents
     P02BX04 Triclabendazole
      D07364  Triclabendazole (USAN/INN) <US>
USP drug classification [BR:br08302]
Antiparasitics
  Anthelmintics
   Triclabendazole
    D07364  Triclabendazole (USAN/INN)
Animal drugs in Japan [BR:br08331]
97  Agents against pathogenic micro-organisms and parasites (except biological products and disinfectants)
  975  Anthelmintics for digestive organs
   9752  Thiabendazole derivatives and preparations
    D07364  Triclabendazole
Antimicrobials [BR:br08307]
Antiparasitics
  Antitrematodal agents
   Others
    D07364  Triclabendazole (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
  D07364
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
  D07364

Other DBs

CAS:	68786-66-3

PubChem:

51091701

PDB-CCD:

JA9[PDBj]

LigandBox:

D07364

NIKKAJI:

J126.317J

KCF data

ATOM        21
            1   C8y C    15.2600  -16.5200
            2   C8x C    15.2600  -17.9200
            3   C8x C    16.4724  -18.6200
            4   C8x C    17.6849  -17.9200
            5   C8y C    17.6849  -16.5200
            6   C8y C    16.4724  -15.8200
            7   X   Cl   16.4724  -14.4202
            8   X   Cl   14.0476  -15.8200
            9   O2a O    18.9160  -15.8090
            10  C8y C    20.1212  -16.5047
            11  C8y C    20.1216  -17.9196
            12  C8x C    21.3342  -18.6193
            13  C8y C    22.5465  -17.9189
            14  C8y C    22.5460  -16.5039
            15  C8x C    21.3334  -15.8043
            16  N5x N    23.8923  -18.3558
            17  C8y C    24.7237  -17.2108
            18  N4x N    23.8916  -16.0663
            19  X   Cl   18.8858  -18.6340
            20  S2a S    26.1100  -17.2104
            21  C1a C    26.8144  -18.4299
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     6   7 1
            8     1   8 1
            9     5   9 1
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   14  15 2
            16   10  15 1
            17   13  16 1
            18   16  17 2
            19   17  18 1
            20   14  18 1
            21   11  19 1
            22   17  20 1
            23   20  21 1