| Entry |
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|---|---|---|---|---|---|---|---|---|---|
| Name | Benzydamine salicylate; Fulgium (TN) | ||||||||
| Formula | C19H23N3O. C7H6O3 | ||||||||
| Exact mass | 447.2158 | ||||||||
| Mol weight | 447.5262 | ||||||||
| Structure |  | ||||||||
| Class | Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) | ||||||||
| Remark |
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| Efficacy | Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor | ||||||||
| Comment | Benzimidazole derivative non-steroidal anti-inflammatory drug (NSAID) | ||||||||
| Target | PTGS1 (COX1) [HSA:5742] [KO:K00509] PTGS2 (COX2) [HSA:5743] [KO:K11987] ALOX5 [HSA:240] [KO:K00461] | ||||||||
| Pathway |
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| Interaction | |||||||||
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] A ALIMENTARY TRACT AND METABOLISM A01 STOMATOLOGICAL PREPARATIONS A01A STOMATOLOGICAL PREPARATIONS A01AD Other agents for local oral treatment A01AD02 Benzydamine (except lozenges) D07517 Benzydamine salicylate G GENITO URINARY SYSTEM AND SEX HORMONES G02 OTHER GYNECOLOGICALS G02C OTHER GYNECOLOGICALS G02CC Antiinflammatory products for vaginal administration G02CC03 Benzydamine D07517 Benzydamine salicylate M MUSCULO-SKELETAL SYSTEM M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS M01AX Other antiinflammatory and antirheumatic agents, non-steroids M01AX07 Benzydamine D07517 Benzydamine salicylate M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02AA Antiinflammatory preparations, non-steroids for topical use M02AA05 Benzydamine D07517 Benzydamine salicylate R RESPIRATORY SYSTEM R02 THROAT PREPARATIONS R02A THROAT PREPARATIONS R02AX Other throat preparetions R02AX03 Benzydamine (only lozenges) D07517 Benzydamine salicylate Drug groups [BR:br08330] Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) DG00014 Benzydamine D07517 Benzydamine salicylate Target-based classification of drugs [BR:br08310] Enzymes Oxidoreductases (EC1) Dioxygenases ALOX5 D07517 Benzydamine salicylate Prostaglandin synthase PTGS1 (COX1) D07517 Benzydamine salicylate PTGS2 (COX2) D07517 Benzydamine salicylate Drug groups [BR:br08330] Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) DG00014 Benzydamine | ||||||||
| Other DBs |
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| KCF data | ATOM 33 1 C8x C 7.1743 -8.7711 2 C8x C 5.9174 -8.0728 3 C8x C 5.9174 -6.6763 4 C8x C 7.1743 -5.9781 5 C8y C 8.3613 -8.0728 6 C8y C 8.3613 -6.6763 7 N4y N 9.6879 -6.1876 8 N5x N 10.5258 -7.3746 9 C8y C 9.6879 -8.4918 10 C1b C 10.5258 -5.0704 11 C8y C 11.9223 -5.0704 12 C8x C 12.6205 -6.3272 13 C8x C 14.0170 -6.3272 14 C8x C 14.7153 -5.0704 15 C8x C 14.0170 -3.8834 16 C8x C 12.6205 -3.8834 17 O2a O 9.6879 -9.8883 18 C1b C 10.8749 -10.5865 19 C1b C 12.1318 -9.8883 20 C1b C 13.2490 -10.5865 21 N1c N 14.5058 -9.8883 22 C1a C 15.6928 -10.5865 23 C1a C 14.5058 -8.4918 24 C8x C 19.0400 -7.7700 25 C8x C 19.0400 -9.1700 26 C8x C 20.2300 -9.8700 27 C8x C 21.4200 -9.1700 28 C8y C 21.4200 -7.7700 29 C8y C 20.2300 -7.0700 30 C6a C 20.2300 -5.6700 31 O6a O 19.0400 -4.9700 32 O6a O 21.4200 -4.9700 33 O1a O 22.6800 -7.0700 BOND 35 1 5 1 1 2 1 2 2 3 10 7 1 4 2 3 1 5 3 4 2 6 5 6 2 7 10 11 1 8 6 7 1 9 7 8 1 10 8 9 2 11 9 5 1 12 4 6 1 13 11 12 2 14 12 13 1 15 13 14 2 16 14 15 1 17 15 16 2 18 16 11 1 19 9 17 1 20 17 18 1 21 18 19 1 22 19 20 1 23 20 21 1 24 21 22 1 25 21 23 1 26 24 25 2 27 25 26 1 28 26 27 2 29 27 28 1 30 28 29 2 31 24 29 1 32 29 30 1 33 30 31 2 34 30 32 1 35 28 33 1 |