Entry

D09219            Mixture   Drug

Name

Telmisartan and hydrochlorothiazide (JP18);
Micombi (TN);
Micardis hct (TN)

Product

MICARDIS HCT (Boehringer Ingelheim Pharmaceuticals)

Generic

TELMISARTAN AND HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals Limited), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Bryant Ranch Prepack), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Cadila Healthcare Limited), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Glenmark Pharmaceuticals), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Hikma Pharmaceuticals USA), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Lupin Pharmaceuticals), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Solco Healthcare LLC), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Zydus Pharmaceuticals (USA)), TELMISARTAN AND HYDROCHLORTHIAZIDE (Torrent Pharmaceuticals Limited)

Component

Telmisartan [DR:D00627], Hydrochlorothiazide [DR:D00340]

Class

Cardiovascular agent
DG01925  Renin-angiotensin system inhibitor
DG03231  Antihypertensive
Metabolizing enzyme substrate
DG02924  UGT substrate

Remark

Therapeutic category:

2149

ATC code:

C09DA07

Product:

D09219<JP/US>

Efficacy

Antihypertensive

Disease

Hypertension [DS:H01633]

Comment

Telmisartan is primarily metabolized by UDP-glucuronosyltransferase (UGT).

Metabolism

Enzyme: UGT [KO:K00699]

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
    C09DA Angiotensin II receptor blockers (ARBs) and diuretics
     C09DA07 Telmisartan and diuretics
      D09219  Telmisartan and hydrochlorothiazide (JP18) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
  Cardiovascular Combinations
   Telmisartan/ Hydrochlorothiazide
    D09219  Telmisartan and hydrochlorothiazide (JP18)
Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D09219  Telmisartan and hydrochlorothiazide (JP18)
Drug groups [BR:br08330]
Cardiovascular agent
  DG01925  Renin-angiotensin system inhibitor
   D09219  Telmisartan and hydrochlorothiazide
  DG03231  Antihypertensive
   D09219  Telmisartan and hydrochlorothiazide
Metabolizing enzyme substrate
  DG02924  UGT substrate
   D09219  Telmisartan and hydrochlorothiazide
Drug classes [BR:br08332]
Cardiovascular agent
  DG03231  Antihypertensive
   D09219  Telmisartan and hydrochlorothiazide
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D09219  Telmisartan and hydrochlorothiazide tablets
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
  D09219
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
  D09219

Other DBs

PubChem:

96025899