| Entry |
|
|---|
| Name |
Chlorpromazine tannate (JAN) |
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG01491 Muscarinic cholinergic receptor antagonist
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
Metabolizing enzyme inhibitor
DG01645 CYP2D6 inhibitor
|
|---|
| Remark |
| Chemical structure group: | DG00867 |
| Product (DG00867): | D00789<JP/US> D04034<JP> |
|
|---|
| Efficacy |
Antipsychotic |
|---|
| Comment |
Phenothiazine derivative
|
|---|
| Target |
HTR2 [HSA:3356 3357 3358] [KO:K04157]
HRH1 [HSA:3269] [KO:K04149]
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
DRD2 [HSA:1813] [KO:K04145]
CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133] |
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04725 | Cholinergic synapse |
| hsa04726 | Serotonergic synapse |
| hsa04728 | Dopaminergic synapse |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA:1565]
|
|---|
| Interaction |
CYP inhibition: CYP2D6 [HSA:1565]
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AA Phenothiazines with aliphatic side-chain
N05AA01 Chlorpromazine
D09819 Chlorpromazine tannate (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
DG01491 Muscarinic cholinergic receptor antagonist
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
Metabolizing enzyme inhibitor
DG01645 CYP2D6 inhibitor
DG00867 Chlorpromazine
D09819 Chlorpromazine tannate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D09819 Chlorpromazine tannate (JAN)
Adrenaline
ADRA2
D09819 Chlorpromazine tannate (JAN)
Dopamine
DRD2
D09819 Chlorpromazine tannate (JAN)
Histamine
HRH1
D09819 Chlorpromazine tannate (JAN)
Serotonin
HTR2
D09819 Chlorpromazine tannate (JAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D09819
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
DG00867 Chlorpromazine
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG00867 Chlorpromazine
DG01491 Muscarinic cholinergic receptor antagonist
DG00867 Chlorpromazine
DG03200 Antipsychotic agent
DG01905 Phenothiazine antipsychotics
DG00867 Chlorpromazine
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00867 Chlorpromazine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00867 Chlorpromazine
Metabolizing enzyme inhibitor
DG01645 CYP2D6 inhibitor
DG00867 Chlorpromazine
|
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| Other DBs |
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