| Entry |
| ||||||
|---|---|---|---|---|---|---|---|
| Name | Omadacycline tosylate (USAN); Nuzyra (TN) | ||||||
| Product | NUZYRA (Paratek Pharmaceuticals) | ||||||
| Formula | C29H40N4O7. C7H8O3S | ||||||
| Exact mass | 728.3091 | ||||||
| Mol weight | 728.8521 | ||||||
| Structure |  | ||||||
| Class | Antibacterial DG01197 Tetracycline antibiotic | ||||||
| Remark |
| ||||||
| Efficacy | Antibiotic, Protein biosynthesis inhibitor | ||||||
| Target | 30S ribosomal subunit | ||||||
| Pathway |
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| Interaction | |||||||
| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01A TETRACYCLINES J01AA Tetracyclines J01AA15 Omadacycline D09940 Omadacycline tosylate (USAN) <US> USP drug classification [BR:br08302] Antibacterials Tetracyclines Omadacycline D09940 Omadacycline tosylate (USAN) Drug groups [BR:br08330] Antibacterial DG01197 Tetracycline antibiotic DG01198 Omadacycline D09940 Omadacycline tosylate Drug classes [BR:br08332] Antibacterial DG01197 Tetracycline antibiotic D09940 Omadacycline tosylate Antimicrobials [BR:br08307] Antibacterials Protein biosynthesis inhibitor Tetracycline D09940 Omadacycline tosylate (USAN) <US> New drug approvals in the USA [br08319.html] New molecular entities and new therapeutic biological products D09940 New drug approvals in the USA, Europe and Japan [br08328.html] Approval dates by FDA, EMA and PMDA D09940 Drug groups [BR:br08330] Antibacterial DG01197 Tetracycline antibiotic DG01198 Omadacycline Antimicrobials abbreviations [BR:br08327] Antibacterials Protein biosynthesis inhibitor Tetracycline DG01198 Omadacycline | ||||||
| Other DBs |
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| KCF data | ATOM 51 1 C8y C 24.3647 -28.8449 2 C8x C 24.3647 -27.4447 3 C8y C 25.5549 -26.7446 4 C8y C 26.8151 -27.4447 5 C8y C 26.8151 -28.8449 6 C8y C 25.5549 -29.5450 7 C1x C 28.0053 -26.7446 8 C1y C 29.1955 -27.4447 9 C2y C 29.1955 -28.8449 10 C5x C 28.0053 -29.5450 11 C1x C 30.5257 -26.7446 12 C1y C 31.7159 -27.4447 13 C1z C 31.7159 -28.8449 14 C2y C 30.5257 -29.5450 15 C1y C 32.9061 -26.7446 16 C2y C 34.1664 -27.4447 17 C2y C 34.1664 -28.8449 18 C5x C 32.9061 -29.5450 19 C1b C 23.1745 -29.5450 20 N1b N 21.9843 -28.8449 21 C1b C 20.7940 -29.5450 22 C1d C 19.6038 -28.8449 23 C1a C 18.4136 -29.5450 24 C1a C 19.6038 -27.4447 25 C1a C 18.3436 -28.1448 26 O5x O 28.0053 -30.9453 27 O1a O 30.5257 -30.9453 28 O1a O 25.5549 -30.9453 29 O5x O 32.9061 -30.9453 30 O1a O 31.7159 -30.2452 31 N1c N 32.9061 -25.3443 32 C5a C 35.3566 -29.5450 33 N1a N 36.5468 -28.8449 34 O5a O 35.3566 -30.9453 35 N1c N 25.5549 -25.3443 36 C1a C 24.3647 -24.6442 37 C1a C 26.7451 -24.6442 38 O1a O 35.3566 -26.7446 39 C1a C 31.7159 -24.6442 40 C1a C 34.0963 -24.6442 41 C8x C 39.2772 -27.4447 42 C8x C 39.2772 -28.8449 43 C8y C 40.4898 -29.5450 44 C8x C 41.7026 -28.8449 45 C8x C 41.7026 -27.4447 46 C8y C 40.4898 -26.7446 47 S4a S 40.4898 -25.3443 48 O1d O 41.8901 -25.3443 49 O1d O 40.4898 -23.9441 50 O1d O 39.0896 -25.3443 51 C1a C 40.4898 -30.9453 BOND 54 1 1 2 1 2 2 3 2 3 3 4 1 4 4 5 2 5 5 6 1 6 1 6 2 7 4 7 1 8 7 8 1 9 8 9 1 10 9 10 1 11 5 10 1 12 8 11 1 13 11 12 1 14 12 13 1 15 13 14 1 16 9 14 2 17 12 15 1 18 15 16 1 19 16 17 2 20 17 18 1 21 13 18 1 22 1 19 1 23 19 20 1 24 20 21 1 25 21 22 1 26 22 23 1 27 22 24 1 28 22 25 1 29 10 26 2 30 14 27 1 31 6 28 1 32 18 29 2 33 13 30 1 #Down 34 15 31 1 #Down 35 17 32 1 36 32 33 1 37 32 34 2 38 3 35 1 39 35 36 1 40 35 37 1 41 16 38 1 42 31 39 1 43 31 40 1 44 41 42 2 45 42 43 1 46 43 44 2 47 44 45 1 48 45 46 2 49 41 46 1 50 46 47 1 51 47 48 2 52 47 49 1 53 47 50 2 54 43 51 1 |