Vutrisiran sodium

Entry

D11916                      Drug

Name

Vutrisiran sodium (JAN);
Amvuttra (TN)

Product

AMVUTTRA (Alnylam Pharmaceuticals)

Formula

C530H672F9N171O323P43S6.43Na

Exact mass

17281.3914

Mol weight

17289.7661

Remark

Chemical structure group:

DG03127

Product (DG03127):

D11916<US>

Efficacy

Gene expression regulator

Disease

Polyneuropathy of hereditary transthyretin-mediated amyloidosis [DS:H00845]

Comment

RNA interference (RNAi) drug
Treatment of transthyretin (TTR)-mediated amyloidosis (ATTR amyloidosis)

Target

TTR [HSA:7276] [KO:K20731] (mRNA)

Pathway

hsa04918

Thyroid hormone synthesis

Brite

Target-based classification of drugs [BR:br08310]
Transporters
  Other transporters
   Others
    TTR
     D11916  Vutrisiran sodium (JAN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
  D11916
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
  D11916