St. John's wort

Entry

D12015            Crude     Drug

Name

St. John's wort;
SJW

Component

Hypericin [CPD:C07606], Pseudohypericin [CPD:C10392], Rutoside [DR:D08499], Hyperin [CPD:C10073], Hyperforin [CPD:C07608], Tannin, Essential oil

Source

Hypericum perforatum [TAX:65561]

Remark

ATC code:

N06AX25

Efficacy

Antidepressant, Hypnotic

Comment

Hypericaceae St. John's wort flowering aerial part
Major component: Hypericin [CPD:C07606]
CYP induction: CYP3A4 [HSA:1576], CYP2C19 [HSA:1557], CYP2C9 [HSA:1559]
Transporter induction: ABCB1 [HSA:5243]

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX25 Hyperici herba
      D12015  St. John's wort
Crude drugs [BR:br08305]
Dicot plants: rosids
  Hypericaceae (hypericum family)
   D12015  St. John's wort