| Entry |
| ||||
|---|---|---|---|---|---|
| Name | Sisunatovir (USAN/INN) | ||||
| Formula | C23H22F4N4O | ||||
| Exact mass | 446.173 | ||||
| Mol weight | 446.4406 | ||||
| Structure |  | ||||
| Remark |
| ||||
| Efficacy | Antiviral, Fusion protein inhibitor | ||||
| Comment | Treatment of respiratory syncytial virus infection | ||||
| Target | RSV F protein [KO:K19261] | ||||
| Brite | Antimicrobials [BR:br08307] Antivirals Entry, fusion or uncoating inhibitor RSV F protein D12200 Sisunatovir (USAN/INN) | ||||
| Other DBs |
| ||||
| KCF data | ATOM 32 1 C8x C 9.4500 -15.8200 2 C8y C 9.4500 -17.2200 3 C8x C 10.6400 -17.9200 4 C8y C 11.9000 -17.2200 5 C8y C 11.9000 -15.8200 6 C8x C 10.6400 -15.1200 7 N5x N 13.2300 -17.6400 8 C8y C 14.0000 -16.5200 9 N4y N 13.2300 -15.4000 10 C1b C 8.2600 -17.9200 11 N1a N 7.0700 -17.2200 12 C1b C 13.6500 -14.0700 13 C1b C 15.0500 -13.7900 14 C1b C 15.9600 -14.8400 15 C1b C 15.4000 -16.5200 16 C1d C 17.3600 -14.5600 17 N1y N 16.1000 -17.7100 18 C5x C 15.6800 -19.0400 19 C1z C 16.8000 -19.8800 20 C8y C 17.9200 -19.1100 21 C8y C 17.5000 -17.7100 22 C8x C 19.2500 -19.3900 23 C8x C 20.2300 -18.3400 24 C8y C 19.7400 -17.0100 25 C8x C 18.4100 -16.7300 26 O5x O 14.3500 -19.3900 27 C1x C 16.1000 -21.0700 28 C1x C 17.5000 -21.0700 29 X F 20.6554 -15.9507 30 X F 18.7123 -14.1977 31 X F 16.9977 -13.2077 32 X F 17.7223 -15.9123 BOND 36 1 1 2 2 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 2 6 1 6 1 7 4 7 1 8 7 8 2 9 8 9 1 10 5 9 1 11 2 10 1 12 10 11 1 13 9 12 1 14 12 13 1 15 13 14 1 16 8 15 1 17 14 16 1 18 15 17 1 19 17 18 1 20 18 19 1 21 19 20 1 22 20 21 1 23 17 21 1 24 20 22 2 25 22 23 1 26 23 24 2 27 24 25 1 28 21 25 2 29 18 26 2 30 27 28 1 31 28 19 1 32 19 27 1 33 24 29 1 34 16 30 1 35 16 31 1 36 16 32 1 |