Nomenclature
CAS number: 21645-51-2
Aluminum hydrate; aluminum trihydrate; hydrated alumina.
AlH
3O
3; mol wt 78.00.
Al 34.59%, H 3.88%, O 61.54%.
Al(OH)
3.
Description and references
Prepn and properties: Dominé-Berges, Ann. Chim. [12] 5, 106 (1950); Hennig, Chem. Tech. 1, 66 (1949); Gmelins, Aluminum (8th ed.) 35B, pp 98-132 (1934); Becher in Handbook
of Preparative Inorganic Chemistry vol. 1,
G. Brauer, Ed. (Academic Press, New York, 2nd ed., 1963) pp 820-821;
Wagner, ibid. vol. 2 (1965) pp 1652-1654. Comparative pharmacology and clinical use
of antacids: F. W. Green, Jr. et
al., Am. J. Hosp. Pharm. 32, 425 (1975). Clinical comparison with
calcium carbonate as phosphate binder in chronic renal failure: R. H. K. Mak et al., Br. Med. J. 291, 623 (1985). Review of use as vaccine adjuvant: W. Nicklas, Res. Immunol. 143, 489-494 (1992).
Properties
Usually obtained as a white, bulky, amorphous
powder. Practically insol in water, but sol in alkaline aq solns or
in HCl, H2SO4 and other strong acids in the
presence of some water. Forms gels on prolonged contact with water.
Absorbs acids, CO2.Derivative
Aluminum hydroxide gel.
Nomenclature
Aldrox (Am. Home); ALternaGEL (J & J-Merck); Aludyal (Sandoz); Amphojel (Wyeth-Ayerst); Cremorin (Sanofi Winthrop); Pepsamar (Sanofi Winthrop); Uracid (Hssle). Properties
White, viscous suspension from which small amounts
of clear liquid may separate on standing. May also be used as the
dried gel. Sol in dilute mineral acids, solns of fixed alkali hydroxides.
Insol in water, alcohol.Use
Adsorbent; emulsifier; ion-exchanger; in chromatography;
mordant in dyeing; filtering medium; manuf glass, fire clay, paper,
pottery, printing inks, lubricating compositions, detergents; waterproofing
fabrics; in antiperspirants, dentifrices. Vaccine adjuvant.
Therapeutic Category
Antacid; antihyperphosphatemic.
Therapeutic Category (Veterinary)
Antacid.
Keywords
Antacid; Antihyperphosphatemic