443. 3-Amino-4-hydroxybutyric Acid

Nomenclature

CAS number: 589-44-6
3-Amino-4-hydroxybutanoic acid; γ-hydroxy-β-aminobutyric acid; GOBAB.
C4H9NO3; mol wt 119.12.
C 40.33%, H 7.62%, N 11.76%, O 40.29%.

Description and references

Prepn: Jollès, Fromageot, Bull. Soc. Chim. Fr. 1951, 862; Chibnall et al., Biochem. J. 68, 122 (1958); Piskov, Zh. Obshch. Khim. 32, 3407 (1962); Nagai et al., Arzneim.-Forsch. 17, 1575 (1967); Kondo, Tanaka, JP 68 12127 (1968 to Kaken Kagaku), C.A. 70, 77328r (1969).

Chemical structure

Properties

Prismatic crystals, mp 216°. Also reported as mp 228° (Nagai); mp 232-233.5° (Chibnall).

Derivative

Hydrochloride.
C4H9NO3.HCl; mol wt 155.58.
C 30.88%, H 6.48%, N 9.00%, O 30.85%, Cl 22.79%.

Properties

mp 156°.

Therapeutic Category

Anti-inflammatory, antifungal.

Keywords

Anti-inflammatory (Nonsteroidal); Antiseptic/Disinfectant