812. Arsthinol

Nomenclature

CAS number: 119-96-0
N-[2-Hydroxy-5-[4-(hydroxymethyl)-1,3,2-dithiarsolan-2-yl]phenyl]acetamide; 3-acetamido-4-hydroxydithiobenzenearsonous acid, cyclic (hydroxymethyl)ethylene ester; 2-(3′-acetamido-4′-hydroxyphenyl)-1,3-dithia-2-arsacyclopentane-4-methanol; 3-acetamido-4-hydroxydithiobenzenearsonous acid cyclic 3-hydroxypropylene ester; 2-acetylamino-4-(methylolcycloethylenedimercaptoarsine)phenol; Balarsen.
C11H14AsNO3S2; mol wt 347.29.
C 38.04%, H 4.06%, As 21.57%, N 4.03%, O 13.82%, S 18.47%.

Description and references

Trivalent arsenical; derivative of acetarsone, q.v. Prepn: Friedheim, US 2593434 (1952); US 2772303 (1956).

Chemical structure

Properties

Minute crystals, mp 163-166°. Soly in 95% ethanol about 2.7% w/v. Very slightly sol in water, ether.

Therapeutic Category

Antiamebic.

Keywords

Antiamebic