1187. Betoxycaine

Nomenclature

CAS number: 3818-62-0
3-Amino-4-butoxybenzoic acid 2-[2-(diethylamino)ethoxy]ethyl ester; 2-diethylaminoethoxyethyl 3-amino-4-butoxybenzoate.
C19H32N2O4; mol wt 352.47.
C 64.74%, H 9.15%, N 7.95%, O 18.16%.

Description and references

Prepn and properties: E. Cuingnet, US 3209022 (1965 to Corbiere). Ionization potential: A. Cier et al., Therapie 26, 941 (1971). Investigations of possible antifibrillatory properties: P. Amaud et al., C. R. Seances Soc. Biol. Ses Fil. 159, 2427 (1965); G. Faucon et al., Therapie 21, 1253 (1966).

Chemical structure

Derivative

Monohydrochloride.

Nomenclature

CAS number: 5003-47-4
Millicaine (Corbiere).
C19H32N2O4.HCl; mol wt 388.93.
C 58.67%, H 8.55%, N 7.20%, O 16.45%, Cl 9.12%.

Properties

White crystals from acetone, mp 117°. Soluble in methanol.

Therapeutic Category

Anesthetic (local).

Keywords

Anesthetic (Local)