1284. Bismuth Subnitrate

Nomenclature

CAS number: 1304-85-4
Bismuth hydroxide nitrate oxide (Bi5(OH)9(NO3)4O); bismuth nitrate basic; bismuth oxynitrate; bismuth subnitricum; bismuthyl nitrate; bismuth white; magistery of bismuth; novismuth; paint white; Spanish white.
Bi5H9N4O22; mol wt 1461.99.
Bi 71.47%, H 0.62%, N 3.83%, O 24.08%.

Description and references

A basic salt, the compn of which varies with the conditions of preparation. Contains 70 to 74% Bi or 79 to 82% Bi2O3. Prepd by partial hydrolysis of Bi(NO3)3: Gmelins, Bismuth (8th ed.) 19, pp 132-135 (1927); Traité Pharm. Chim. vol. 1, P. Lebeau, M. M. Janot, Eds. (Masson, Paris, 1956) p 371; Handbuch der Pharmazie vol. 4(1), H. Thoms, Ed. (Urban & Schwarzenberg, Berlin, 1927) p 325. Mechanism of action study: S. Pugh, M. R. Lewin, J. Gastroenterol. Hepatol. 5, 382 (1990). Clinical studies in ulcer caused by Helicobacter pylori infection: A. F. Carvalho et al., Aliment. Pharmacol. Ther. 12, 557 (1998); M. W. Whitehead et al., Helicobacter 5, 169 (2000); R. H. Phillips et al., ibid. 176.

Properties

Odorless, tasteless, heavy, slightly hygroscopic, microcrystalline powder. Dec to Bi2O3 and nitrogen oxides when heated to red heat. Practically insol in water, alc. Sol in dil HCl and HNO3. Keep well closed and protect from light. Incompat. Alkaline bicarbonates, soluble iodides, gallic acid, calomel, salicylic acid, tannin, sulfur.

Use

Manuf bismuth fluxes for enamels; in cosmetics.

Therapeutic Category

Antacid; antiulcerative.

Therapeutic Category (Veterinary)

See Bismuth.

Keywords

Antacid; Antiulcerative