1413. α-Bromobutyric Acid

Nomenclature

CAS number: 80-58-0
2-Bromobutanoic acid; dl-2-bromobutyric acid.
C4H7BrO2; mol wt 167.00.
C 28.77%, H 4.22%, Br 47.85%, O 19.16%.

Description and references

Prepd by bromination of butyric acid: Naumann, Ann. 119, 115 (1861); Stevens, Holland, J. Org. Chem. 18, 1112 (1953); Smissman, J. Am. Chem. Soc. 76, 5805 (1954). Toxicity study: J. L. Morrison, J. Pharmacol. Exp. Ther. 86, 336 (1946).

Chemical structure

Properties

Oily liquid, mp 4°. bp250 181-182°, bp25 127-128°. d44 1.5855, d1515 1.5735, d2020 1.5669, d2525 1.5620: Perkin, J. Chem. Soc. 65, 402 (1894). Boils with decompn at ordinary pressure. Sol in 15 parts water; sol in alcohol, ether. Corrosive. LD50 orally in mice: 310 mg/kg (Morrison).

Derivative

Ethyl ester.

Nomenclature

CAS number: 533-68-6
Ethyl α-bromobutyrate.
C6H11BrO2; mol wt 195.05.
C 36.95%, H 5.68%, Br 40.97%, O 16.41%.

Properties

Liquid, bp 177-178° with slight dec. d2020 1.329. Insol in water. Misc with alc, ether. Protect from light. Lacrimator.