1513. Butamirate

Nomenclature

CAS number: 18109-80-3
α-Ethylbenzeneacetic acid 2-[2-(diethylamino)ethoxy]ethyl ester; 2-phenylbutyric acid 2-[2-(diethylamino)ethoxy]ethyl ester; 2-[2-(diethylamino)ethoxy]ethyl 2-phenylbutyrate; butamyrate.
C18H29NO3; mol wt 307.43.
C 70.32%, H 9.51%, N 4.56%, O 15.61%.

Description and references

Prepd by the esterification of phenylethylacetyl chloride with diethylaminoethoxyethanol: DE 1151515; Heusser, US 3349114 (1963, 1967, both to Hommel A.G.).

Chemical structure

Properties

Practically colorless liquid with peculiar odor. bp1 140-155°. Practically insol in water. Very sol in alcohol, acetone, ether.

Derivative

Citrate.

Nomenclature

CAS number: 18109-81-4
Abbott 36581; HH-197; Acodeen (Hommel); Panatus (Krka); Sincodix (Beta); Sinecod (Zyma).
C18H29NO3.C6H8O7; mol wt 499.55.
C 57.70%, H 7.47%, N 2.80%, O 32.03%.

Properties

White, hygroscopic crystals from acetone, mp 75°.

Therapeutic Category

Antitussive.

Keywords

Antitussive