1514. Butamisole

Nomenclature

CAS number: 54400-59-8
2-Methyl-N-[3-[(6S)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazol-6-yl]phenyl]propanamide; (-)-2-methyl-3′-(2,3,5,6-tetrahydroimidazo[2,1-b]thiazol-6-yl)propionanilide.
C15H19N3OS; mol wt 289.40.
C 62.25%, H 6.62%, N 14.52%, O 5.53%, S 11.08%.

Description and references

Prepn: L. D. Spicer, J. J. Hand, ZA 7105803 (1972 to Am. Cyanamid), C.A. 78, 72151h (1973). Prepn and resolution of isomers: eidem, FR 2199979; eidem, US 3899583 (1974, 1975 both to Am. Cyanamid). Efficacy and safety in dogs: B. T. Alford et al., Vet. Med. Small Anim. Clin. 74, 487 (1979). Evaluation in horses and ponies: R. B. Grieve et al., Am. J. Vet. Res. 40, 139 (1979).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 54400-62-3
CL-206214; Styquin.
C15H19N3OS.HCl; mol wt 325.86.
C 55.29%, H 6.19%, N 12.90%, O 4.91%, S 9.84%, Cl 10.88%.

Therapeutic Category (Veterinary)

Anthelmintic.