1665. Calcium Cyclamate

Nomenclature

CAS number: 139-06-0
Cyclohexylsulfamic acid calcium salt; cyclohexanesulfamic acid calcium salt; calcium cyclohexanesulfamate; calcium cyclohexylsulfamate; cyclamate calcium; Cyclan; Sucaryl Calcium (Abbott).
C12H24CaN2O6S2; mol wt 396.54.
C 36.35%, H 6.10%, Ca 10.11%, N 7.06%, O 24.21%, S 16.17%.
[C6H11NHSO3-]2Ca2+.

Description and references

Prepn: Cummins, Johnson; McQuaid, US 2799700; US 2804477 (both 1957 to du Pont); Freifelder, US 3082247 (1963 to Abbott); Birsten, Rosin, US 3361798; US 3366670 (both 1968 to Baldwin-Montrose). Metabolism: Wallace et al., J. Pharmacol. Exp. Ther. 175, 325 (1970); Prosky, O'Dell, J. Pharm. Sci. 60, 1341 (1971); Renwick, Williams, Biochem. J. 129, 869 (1972). See also Cyclamic Acid.

Derivative

Dihydrate.

Properties

Crystals with pleasant, very sweet taste. Freely sol in water. Practically insol in alc, benzene, chloroform, ether. pH of 10% aq soln 5.5-7.5. Said to be more resistant to cooking temps than saccharin.

Note

Consult latest Government regulations on use in foods.

Use

Non-nutritive sweetener.