Nomenclature
CAS number: 124-43-6
Urea compd with hydrogen peroxide (1:1); urea hydrogen peroxide; Debrox (SKB); Exterol (Dermal); Gly-Oxide (SKB); Hyperol (Gedeon Richter); Ortizon (obsolete) (Bayer AG).
CH
6N
2O
3; mol wt 94.07.
C 12.77%, H 6.43%, N 29.78%, O 51.02%.
CO(NH
2)
2.H
2O
2.
Description and references
Prepn: GB 1555 (1911 to Bayer); M. Strauss, Chem. Zentralbl. 11, 820 (1913).
Use for prepn of H2O2: J. Milbauer, Chem. Ztg. 35, 871 (1911), C.A. 5, 3391 (1911). Clinical
trial in aphthous stomatitis: M. F. Miller, N. W. Chilton, Pharmacol. Ther. Dent. 5, 55 (1980);
as cerumenolytic: S. Fahmy, M. Whitefield, Br. J. Clin. Pract. 36, 197 (1982); as dental
bleach: V. B. Haywood et al., J. Am. Dent. Assoc. 125, 1219 (1994).
Properties
White crystals or cryst powder. Dec in air into
urea, oxygen, and water. Sol in 2.5 parts water; partly dec by alcohol
and ether into H2O2 and urea.Use
For extemporaneous prepn of H
2O
2.
Therapeutic Category
Antiseptic; cerumenolytic; dental bleach.
Keywords
Antiseptic/Disinfectant; Peroxides/Permanganates