1805. γ-Carboline

Nomenclature

CAS number: 244-69-9
5H-Pyrido[4,3-b]indole; 2H-pyrid[4,3-b]indole; 5-carboline.
C11H8N2; mol wt 168.19.
C 78.55%, H 4.79%, N 16.66%.

Description and references

Prepn: Robinson, Thornley, J. Chem. Soc. 125, 2169 (1924). Prepn of derivs: H"orlein, Ber. 87, 463 (1954); C. Ducrocq et al., J. Heterocycl. Chem. 12, 963 (1975). NMR studies: F. Balkau, M. L. Heffernan, Aust. J. Chem. 26, 1501, 1523 (1973).

Chemical structure

Properties

Monoclinic needles from water, mp 225°. d 1.352. Can be distilled at atmospheric pressure without dec. Strong base. Freely sol in methanol; somewhat less sol in ethanol. Slightly sol in benzene, water.