2017. Cetalkonium Chloride

Nomenclature

CAS number: 122-18-9
N-Hexadecyl-N,N-dimethylbenzenemethanaminium chloride; benzylhexadecyldimethylammonium chloride; cetyldimethylbenzylammonium chloride; hexadecyldimethylbenzylammonium chloride; Banicol; Acetoquat CDAC; Acquat CDAC; Ammonyx G; Zettyn; Ammonyx T; Cetol.
C25H46ClN; mol wt 396.09.
C 75.81%, H 11.71%, Cl 8.95%, N 3.54%.

Description and references

Prepn: FR 771746 (1934 to I. G. Farben); Piggott, US 2075958 (1937 to I.C.I.); Westphal, Jerchel, Ber. 73, 1011 (1940). Review of this type of quaternary ammonium compounds: J. P. Sisley, P. J. Wood, Encyclopedia of Surface-Active Agents (Chem. Publishing Co., New York, 1952) p 96 sqq.

Chemical structure

Properties

Leaflets from ethyl acetate + petr ether, mp 59°. Sol in water, alc, acetone, ethyl acetate, propylene glycol, sorbitol solns, glycerol, ether, CCl4. pH of aq solns 7.2.

Use

Cationic quaternary ammonium surfactant germicide and fungicide. Used in leather processing, textile dyeing. A mildew preventive in silicone-based water repellents. Compatible with many nonionic detergents. Active in moderately alkaline solns.

Therapeutic Category

Anti-infective (topical).

Keywords

Antiseptic/Disinfectant; Quaternary Ammonium Compounds