2074. Chloramine-B

Nomenclature

CAS number: 127-52-6
N-Chlorobenzenesulfonamide sodium salt (1:1); (N-chlorobenzenesulfonamido)sodium; sodium benzenesulfochloramine; Neomagnol (Chinoin).
C6H5ClNNaO2S; mol wt 213.62.
C 33.73%, H 2.36%, Cl 16.60%, N 6.56%, Na 10.76%, O 14.98%, S 15.01%.

Description and references

Prepd via benzenesulfonamide: Chattaway, J. Chem. Soc. 87, 145 (1905); Cuiban et al., Pharmazie 13, 407 (1958).

Chemical structure

Derivative

Trihydrate.

Nomenclature

CAS number: 17440-73-2
C6H5ClNNaO2S.3H2O; mol wt 267.66.
C 26.92%, H 4.14%, Cl 13.25%, N 5.23%, Na 8.59%, O 29.89%, S 11.98%.

Properties

Prisms. Corrosive. Soluble in 20 parts of water, more sol in hot water. Sol in 25 parts of ethanol, yielding a turbid soln. Very sparingly sol in ether, chloroform. An aq soln first turns red litmus paper blue, then gradually bleaches it. Gives a red color wth phenolphthalein.

Therapeutic Category

Antibacterial.

Therapeutic Category (Veterinary)

Antiseptic (topical).

Keywords

Antibacterial (Synthetic); Sulfonamides