2175. Chloroxine

Nomenclature

CAS number: 773-76-2
5,7-Dichloro-8-quinolinol; 5,7-dichloro-8-hydroxyquinoline; Capitrol (Westwood).
C9H5Cl2NO; mol wt 214.05.
C 50.50%, H 2.35%, Cl 33.13%, N 6.54%, O 7.47%.

Description and references

Prepd by chlorinating 8-quinolinol: Hebebrand, Ber. 21, 2977 (1888), F. J. Welcher, Organic Analytical Reagents vol. I (Van Nostrand, 1947) pp 328-329.

Chemical structure

Properties

Crystals from alc, mp 179-180°. Soluble in benzene, acetone; slightly sol in cold alcohol, acetic acid; readily sol in sodium and potassium hydroxides and in acids, forming yellow solns.

Use

Analytical reagent.

Therapeutic Category

Antiseborrheic.

Keywords

Antiseborrheic; Antiseptic/Disinfectant; Quinolines